视力丧失和光学相干断层扫描（OCT）变化作为白血病的初始体征
Visual acuity loss and OCT changes as initial signs of leukaemia.
作者信息
Ortiz Jose M, Ruiz-Moreno Jose M, Pozo-Martos Paola, Montero Javier A
机构信息
Department of Ophthalmology and Albacete Hospital, Castilla La Mancha University. Albacete. Spain.
出版信息
Int J Ophthalmol. 2010;3(3):281-2. doi: 10.3980/j.issn.2222-3959.2010.03.24. Epub 2010 Sep 18.
AIM
To report two cases where decreased visual acuity was the first symptom of leukaemia and optical coherence tomography (OCT) allowed identification and localization of the retinal lesions.
METHODS
Retrospective, interventional, case reports.
RESULTS
One case of lymphoblastic acute leukaemia and chronic lymphoid leukaemia were diagnosed following decreased visual acuity. OCT showed macular serous detachment in the first case. The second case presented hypo fluorescent retinal infiltrates which appeared as hyper reflective lesions by OCT. Retinal changes disappeared and visual acuity was recovered following complete remission of the neoplasm.
CONCLUSION
OCT is a valuable, non invasive diagnostic tool permitting detection, localization and follow-up of ocular dissemination of neoplasms.
目的
报告两例以视力下降为白血病首发症状且光学相干断层扫描（OCT）可实现视网膜病变识别与定位的病例。
方法
回顾性、介入性病例报告。
结果
1例淋巴细胞性急性白血病和1例慢性淋巴细胞白血病在视力下降后被诊断出来。OCT在第一例中显示黄斑浆液性脱离。第二例呈现视网膜低荧光浸润，在OCT上表现为高反射性病变。肿瘤完全缓解后，视网膜病变消失且视力恢复。
结论
OCT是一种有价值的非侵入性诊断工具，可用于检测、定位和随访肿瘤的眼部播散。
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