Ng Danny Siu-Chun, Chan Edwin, Yau Kin, Chan Clement Wai-Nang
Department of Ophthalmology, Tung Wah Eastern Hospital, Hong Kong, China.
Int J Ophthalmol. 2011;4(3):311-3. doi: 10.3980/j.issn.2222-3959.2011.03.21. Epub 2011 Jun 18.
To survey the clinicopathological correlations of lacrimal fossa lesions in the Hong Kong population.
A total of 23 patients with lacrimal fossa lesions were identified radiologically. The mean age at the time of diagnosis was 52 year-old. The medical records of patients diagnosed with lacrimal fossa lesions and subsequently underwent radiological investigations were collected and reviewed retrospectively throughout a six years period from 2000 to 2006 from three regional hospitals (Tung Wah Eastern Hospital, Pamela Youde Nethersole Eastern Hospital and Queen Mary Hospital) belonging to the Hong Kong Mega Cluster. Patient demographics, presenting signs and symptoms, imaging modalities, pathological reports and subsequent management were recorded.
The most common initial presenting symptom was upper lid swelling (83%) followed by proptosis (13%). 19 patients (83%) had benign lacrimal fossa lesion and 4 patients (17%) had malignancy. Three of the malignancies were lymphomas and one was adenoid cystic carcinoma.
Age is an important factor in considering the differential diagnosis of lacrimal fossa lesion. Lymphoproliferative diseases have the highest incidence in patients over 60 years of age while inflammatory lesions are more common in younger patients in Hong Kong.
调查香港人群泪腺窝病变的临床病理相关性。
通过影像学检查共确定了23例泪腺窝病变患者。诊断时的平均年龄为52岁。收集并回顾了2000年至2006年期间来自香港大型医疗集团旗下三家地区医院(东华东院、东区尤德夫人那打素医院和玛丽医院)的被诊断为泪腺窝病变并随后接受影像学检查的患者的病历。记录了患者的人口统计学资料、出现的体征和症状、成像方式、病理报告及后续治疗情况。
最常见的初始症状是上睑肿胀(83%),其次是眼球突出(13%)。19例患者(83%)患有良性泪腺窝病变,4例患者(17%)患有恶性病变。其中3例恶性病变为淋巴瘤,1例为腺样囊性癌。
年龄是考虑泪腺窝病变鉴别诊断的一个重要因素。在香港,淋巴增生性疾病在60岁以上患者中发病率最高,而炎症性病变在年轻患者中更为常见。