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泪腺窝病变:埃及146例病例回顾

Lacrimal fossa lesions: a review of 146 cases in Egypt.

作者信息

Eldesouky Mohammed A, Elbakary Molham A, Sabik Saly, Shareef Mohamed M

机构信息

Oculoplastic Unit, Ophthalmology Department, Faculty of Medicine, Tanta University, Tanta, Egypt.

Pathology Department, Faculty of Medicine, Tanta University, Tanta, Egypt.

出版信息

Clin Ophthalmol. 2014 Aug 26;8:1603-9. doi: 10.2147/OPTH.S64703. eCollection 2014.

Abstract

PURPOSE

The incidence and clinical and imaging criteria of different pathological forms of lacrimal fossa lesions in the Delta region of Egypt were studied.

METHODS

A retrospective study of patients with lacrimal fossa lesions for the past 10 years was conducted. A total of 146 cases were identified. Their medical records were reviewed for clinical and imaging data (computed tomography scan, magnetic resonance imaging scan, or both). A definitive diagnosis based on pathological examination of biopsies was also reviewed.

RESULTS

Among the patients reviewed, 43.15% had inflammatory lacrimal gland lesions, 26.71% had lymphoproliferative lesions, and 21.92% had epithelial lesions; 8.22% had rare lesions (5.48% were dacryops and 2.74% had hemangioma). The study included 71.92% benign lesions and 28.08% malignant lesions, which were distributed between 19.18% malignant lymphoma and 8.9% malignant epithelial tumors. According to the pathological origin of the lesions, they may be classified into 78.08% nonepithelial lesions and 21.92% epithelial lesions (16.44% epithelial tumors, and 5.48% dermoid cysts).

CONCLUSION

Lacrimal fossa lesions show a wide pathological range. Inflammatory lesions are most frequent, followed by lymphoproliferative and epithelial lesions. Analysis of clinical and radiological criteria is helpful in the differential diagnosis of lacrimal gland lesions.

摘要

目的

研究埃及三角洲地区泪腺窝病变不同病理类型的发病率、临床及影像学标准。

方法

对过去10年中患有泪腺窝病变的患者进行回顾性研究。共确定146例病例。查阅他们的病历以获取临床和影像学数据(计算机断层扫描、磁共振成像扫描或两者皆有)。还查阅了基于活检病理检查的明确诊断。

结果

在回顾的患者中,43.15%患有炎性泪腺病变,26.71%患有淋巴增生性病变,21.92%患有上皮性病变;8.22%患有罕见病变(5.48%为泪腺囊肿,2.74%患有血管瘤)。该研究包括71.92%的良性病变和28.08%的恶性病变,其中恶性淋巴瘤占19.18%,恶性上皮性肿瘤占8.9%。根据病变的病理起源,可分为78.08%的非上皮性病变和21.92%的上皮性病变(16.44%为上皮性肿瘤,5.48%为皮样囊肿)。

结论

泪腺窝病变显示出广泛的病理范围。炎性病变最为常见,其次是淋巴增生性和上皮性病变。分析临床和放射学标准有助于泪腺病变的鉴别诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d2c/4155806/e67ff88b31e0/opth-8-1603Fig1.jpg

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