Zhong Yi-Sheng, Chen Li-Ping, Cheng Yu
Department of Ophthalmology, Ruijin Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai 200025, China.
Int J Ophthalmol. 2011;4(6):623-6. doi: 10.3980/j.issn.2222-3959.2011.06.09. Epub 2011 Dec 18.
To evaluate the frequency of blue-on-yellow perimetry (B/YP) deficits in ocular hypertension (OHT) patients and to correlate these findings with central corneal thickness (CCT), and to investigate the influence of age, refraction and gender on the B/YP results in OHT patients.
The B/YP and CCT were checked respectively in 72 OHT patients with normal white-on-white perimetry(W/WP) and normal optic nerve head. The B/YP was tested by Octopus 101 automated perimetry using G2 strategy, while the CCT was checked with DGH-550 ultrasound pachymeter. All patients were chosen randomly one eye for statistical analysis, a binary regression model was used to determine the independent contribution of variables included in the model, and the differences of the intraocular pressure (IOP), CCT, age, refraction and gender between the normal B/YP group and abnormal B/YP group were compared.
Forty-nine out of 72 patients with OHT showed normal B/YP results, whereas 23 of 72 patients(31.9%) demonstrated abnormal B/YP results. CCT showed a correlation with the B/YP results (B=-0.038, SE=0.019, P=0.044), whereas none of the IOP, age, refraction and gender was found to be correlated with the B/YP results. The mean CCT in OHT patients with abnormal B/YP group was lower than that with normal B/YP group (t=2.066, P=0.043).There was a significant positive correlation between IOP and CCT (R(2)=0.513, P=0.000).
The mean CCT in OHT patients with abnormal B/YP results was lower than that with normal B/YP results. There was a significant positive correlation between IOP and CCT in OHT patients. The age, refraction and gender didn't influence the B/YP results in OHT patients.
评估高眼压症（OHT）患者蓝黄视野检查（B/YP）缺损的发生率，并将这些结果与中央角膜厚度（CCT）相关联，同时研究年龄、屈光状态和性别对OHT患者B/YP检查结果的影响。
对72例白色对白色视野检查（W/WP）正常且视神经乳头正常的OHT患者分别进行B/YP检查和CCT测量。使用Octopus 101自动视野计采用G2策略进行B/YP检查，同时用DGH - 550超声角膜测厚仪测量CCT。所有患者随机选取一只眼进行统计分析，采用二元回归模型确定模型中各变量的独立作用，并比较正常B/YP组和异常B/YP组之间的眼压（IOP）、CCT、年龄、屈光状态和性别的差异。
72例OHT患者中，49例B/YP检查结果正常，而72例患者中的23例（31.9%）B/YP检查结果异常。CCT与B/YP检查结果相关（B = -0.038，标准误 = 0.019，P = 0.044），而IOP、年龄、屈光状态和性别均与B/YP检查结果无关。异常B/YP组OHT患者的平均CCT低于正常B/YP组（t = 2.066，P = 0.043）。IOP与CCT之间存在显著正相关（R² =
0.513，P = 0.000）。
B/YP检查结果异常的OHT患者的平均CCT低于检查结果正常的患者。OHT患者的IOP与CCT之间存在显著正相关。年龄、屈光状态和性别不影响OHT患者的B/YP检查结果。
