板层角膜移植术后泪膜的临床分析
Clinical analysis of tear film after lamellar keratoplasty.
作者信息
Huang Wan-Rong, Chen Qiu-Lian, Cai Jin-Hong, Zhang Yue
机构信息
Xiamen Eye Center of Xiamen University, Xiamen 361001, Fujian Province, China.
出版信息
Int J Ophthalmol. 2012;5(1):74-5. doi: 10.3980/j.issn.2222-3959.2012.01.15. Epub 2012 Feb 18.
AIM
To study the tear film stability after lamellar keratoplasty.
METHODS
Five female and eight male patients with lamellar keratoconus, aged from 18 to 32, were involved. After lamellar keratoplasty, Schirmer I test(S I t), tear break-up time(BUT) test, fluorescein staining test were used to judge the effect of the surgery at different time point.
RESULTS
The S I t were greatly increased in 7 days post operation (11.86±2.28 -25.14±1.97, 19.86±1.61) (P<0.05), there is no significant difference between 2(nd) month, 3(rd) month post-operative and pre-operation (11.86±2.28 - 14.57±1.48, 8.14±0.86) (P>0.05). The mean break-up time decreased in 7 days post operation (5.00±1.31 - 2.71±0.18, 2.57±0.20, 2.71±0.36, 2.43±0.20) (P<0.05). The mean scores of fluorescence increased post-operatively (0.14±0.14 - 8.00±0.00, 8.00±0.00, 8.00±0.00, 7.57±0.20) (P<0.01).
CONCLUSION
Lamellar keratoplaty influence the tear film stability, artificial tears and improving corneal epithelium cured medicine should be used after surgery.
目的
研究板层角膜移植术后泪膜稳定性。
方法
纳入5名女性和8名男性板层圆锥角膜患者，年龄在18至32岁之间。板层角膜移植术后，在不同时间点采用泪液分泌试验（SIt）、泪膜破裂时间（BUT）试验、荧光素染色试验来判断手术效果。
结果
术后7天泪液分泌试验值显著升高（11.86±2.28 - 25.14±1.97，19.86±1.61）（P<0.05），术后第2个月、第3个月与术前相比无显著差异（11.86±2.28 - 14.57±1.48，8.14±0.86）（P>0.05）。术后7天平均泪膜破裂时间缩短（5.00±1.31 - 2.71±0.18，2.57±0.20，2.71±0.36，2.43±0.20）（P<0.05）。荧光素染色平均得分术后升高（0.14±0.14 - 8.00±0.00，8.00±0.00，8.00±0.00，7.57±0.20）（P<0.01）。
结论
板层角膜移植影响泪膜稳定性，术后应使用人工泪液及促进角膜上皮修复的药物。
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