Ortiz-Galeano I, Franquelo-Morales P, Notario-Pacheco B, Nieto Rodríguez J A, Ungría Cañete M V, Martínez-Vizcaíno V
Centro de Estudios Sociosanitarios, Facultad de Enfermería, Universidad de Castilla-La Mancha, Cuenca, España.
Rev Clin Esp. 2012 Jun;212(6):287-91. doi: 10.1016/j.rce.2012.03.008. Epub 2012 May 2.
Prehypertension is a new category of blood pressure and is considered a cardiovascular risk factor. This study has aimed to estimate the prevalence of prehypertension and the association between prehypertension and other vascular risk factors in young adults.
First year university students from all areas of study in the University of Cuenca were invited to participate. Prehypertension was defined as systolic blood pressure between 120-139 mmHg and/or diastolic blood pressure between 80-89 mmHg. Anthropometric, lipid and metabolic variables were measures. The presence of metabolic syndrome was evaluated and quantified based on the sum of the standardized scores of the waist circumference, the triglyceride/c-HDL ratio, mean blood pressure and R-HOMA (Index of insulin resistance to glucose lowering effect).
A total of 545 university students were included in the analysis (mean age 20.36±3.9 years, 74.7% women). Prehypertension prevalence was 24% (95% CI: 21-27%), (56.5% in men and 13% in women). The condition of prehypertension was directly associated to the body mass index (OR: 1.194; 95% CI: 1.124-1.311), insulin resistance (R-HOMA, OR: 2.638; 95% CI: 1.263-4.926) and to the index or quantification of the severity of the metabolic syndrome (OR: 4-868; 95% CI: 3-846-8-328). On the other hand, HDL-c showed an inverse relationship with prehypertension (OR: 0.981; 95% CI: 0.957-0.993).
One out of every four young adults presents prehypertension. This condition is associated to well-established vascular risk factors.
高血压前期是一种新的血压类别,被视为心血管危险因素。本研究旨在评估年轻成年人中高血压前期的患病率以及高血压前期与其他血管危险因素之间的关联。
邀请了昆卡大学所有专业的一年级学生参与。高血压前期定义为收缩压在120 - 139 mmHg之间和/或舒张压在80 - 89 mmHg之间。测量了人体测量学、血脂和代谢变量。基于腰围、甘油三酯/高密度脂蛋白胆固醇比值、平均血压和R - HOMA(胰岛素抵抗对葡萄糖降低作用指数)的标准化得分总和,评估并量化代谢综合征的存在情况。
共有545名大学生纳入分析(平均年龄20.36±3.9岁,74.7%为女性)。高血压前期患病率为24%(95%置信区间:21 - 27%),(男性为56.5%,女性为13%)。高血压前期状况与体重指数直接相关(比值比:1.194;95%置信区间:1.124 - 1.311)、胰岛素抵抗(R - HOMA,比值比:2.638;95%置信区间:1.263 - 4.926)以及代谢综合征严重程度指数或量化指标相关(比值比:4 - 868;95%置信区间:3 - 846 - 8 - 328)。另一方面,高密度脂蛋白胆固醇与高血压前期呈负相关(比值比:0.981;95%置信区间:0.957 - 0.993)。
每四名年轻成年人中就有一人患有高血压前期。这种状况与已确定的血管危险因素相关。