Ríos-González Blanca Estela, Saldaña-Cruz Ana Míriam, Gallardo-Moya Sergio Gabriel, Brambila-Tapia Aniel Jessica Leticia
Unidad Médico Familiar #92, Instituto Mexicano del Seguro Social (IMSS), Guadalajara 44340, Mexico.
Especialidad en Medicina Familiar, Centro Universitario de Ciencias de la Salud (CUCS), Universidad de Guadalajara, Guadalajara 44340, Mexico.
J Clin Med. 2024 Jan 10;13(2):378. doi: 10.3390/jcm13020378.
Hypertension is one of the main risk factors related to cardiovascular mortality, being the levels of blood pressure (BP) related to a variety of personal, anthropometric, biochemical and psychological variables; however, the study evaluating the association of all these factors in systolic blood pressure (SBP) and diastolic blood pressure (DBP) in a sample of relatively healthy subjects has not been performed. The aim of the study was to determine the main variables associated with SBP and DPB in a sample of relatively healthy subjects. A total of 171 participants were included, in which personal, anthropometric, positive and negative psychological variables and biochemical variables were measured. We observed that men showed higher levels of SBP and DBP than women, with more differences for SBP. Among the biochemical factors and SBP, we found that albumin and monocytes were positively correlated with it, while potassium, phosphorus and eosinophils were negatively correlated with it. Additionally, schooling was a constant variable negatively correlated with SBP in all samples (global, men and women). Among psychological variables, we observed that emotional perception was negatively correlated with SBP in men's and women's samples, while autonomy was positively correlated with SBP in the men's sample; however, their association was less when compared with the personal and biochemical variables included in the multivariate model. With regard to DBP, we observed that the biochemical variables, hemoglobin, sodium, uric acid and glucose, were positively correlated with DBP in the global sample, while chloride and BUN were negatively correlated with it. In addition, many personal and behavioral variables, including BMI, age and smoking consumption frequency, also correlated with DBP in the global sample. In conclusion, BP is affected by different factors, and these affect each sex differently.
高血压是心血管疾病死亡率的主要风险因素之一，血压水平与各种个人、人体测量、生化和心理变量相关；然而，尚未对相对健康的受试者样本中所有这些因素与收缩压（SBP）和舒张压（DBP）之间的关联进行研究。本研究的目的是确定相对健康的受试者样本中与SBP和DBP相关的主要变量。共纳入171名参与者，测量了他们的个人、人体测量、正负心理变量和生化变量。我们观察到，男性的SBP和DBP水平高于女性，SBP的差异更大。在生化因素与SBP之间，我们发现白蛋白和单核细胞与之呈正相关，而钾、磷和嗜酸性粒细胞与之呈负相关。此外，在所有样本（总体、男性和女性）中，受教育程度是与SBP呈负相关的恒定变量。在心理变量方面，我们观察到，在男性和女性样本中，情绪感知与SBP呈负相关，而在男性样本中自主性与SBP呈正相关；然而，与多变量模型中纳入的个人和生化变量相比，它们之间的关联较小。关于DBP，我们观察到，在总体样本中，生化变量血红蛋白、钠、尿酸和葡萄糖与DBP呈正相关，而氯和尿素氮与之呈负相关。此外，许多个人和行为变量，包括BMI、年龄和吸烟频率，在总体样本中也与DBP相关。总之，血压受不同因素影响，且这些因素对不同性别影响各异。
