Department of Dermatology, Trang Hospital, Trang, Thailand.
Am J Trop Med Hyg. 2012 May;86(5):821-4. doi: 10.4269/ajtmh.2012.11-0707.
We report the first establishment of in vitro cultivation and genotypic characterization of Leishmania siamensis isolated from an autochthonous disseminated dermal and visceral leishmaniasis in a Thai acquired immunodeficiency syndrome (AIDS) patient. The molecular identification has shown that the parasite was identical to L. siamensis, a recently described Leishmania species reported in the southern provinces of Thailand. The phylogenetic analysis has confirmed L. siamensis as closely related to the zoonotic Leishmania species L. enrietti.
我们报告了首例从泰国获得性免疫缺陷综合征(AIDS)患者的原发性皮肤和内脏利什曼病中分离出的利什曼原虫暹罗种的体外培养和基因特征分析。分子鉴定表明,该寄生虫与利什曼原虫暹罗种完全一致,这是一种最近在泰国南部省份报道的利什曼新种。系统发育分析证实,利什曼原虫暹罗种与动物源性利什曼种利什曼原虫密切相关。