Mar'iandyshev A O, Tikhonov V A, Evsraf'ev Iu A, Grigor'ev Iu G
Probl Tuberk. 1990(8):32-4.
Effects of apressin, a peripheral vasodilator, on external respiration function and central hemodynamics was studied in 51 patients with pulmonary tuberculosis. The study showed that a single administration of 20 mg apressin in pulmonary tuberculosis patients failed to bring about any changes in both external respiration function and blood gases, only causing a minor shift in the buffer bases. Systolic pressure in the pulmonary artery remained unchanged after a single 20 mg dose of apressin was given. A statistically significant decrease in total pulmonary vascular resistance and an increase of the central hemodynamic values in pulmonary tuberculosis patients with hypokinetic type of circulation are recorded.
对51例肺结核患者研究了外周血管扩张剂阿普加压素对外呼吸功能和中心血流动力学的影响。研究表明，肺结核患者单次给予20毫克阿普加压素后，外呼吸功能和血气均未发生任何变化，仅缓冲碱有轻微改变。单次给予20毫克阿普加压素后，肺动脉收缩压保持不变。在循环动力不足型的肺结核患者中，记录到总肺血管阻力有统计学意义的下降以及中心血流动力学值增加。
