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Congenital acute megakaryocytic leukemia.

作者信息

Mathur N B, Joshi Neha, Singh T, Singh Meeta

机构信息

Department of Pediatrics, Maulana Azad Medical College, Delhi, India.

出版信息

Indian J Med Paediatr Oncol. 2011 Jul;32(3):165-7. doi: 10.4103/0971-5851.92821.

Abstract

Congenital leukemia (CL) is an extremely rare disorder in the newborn, significant proportion of which is of myeloid origin, primarily of M4 or M5 morphology. As compared to pediatric leukemia, CL is a more aggressive disease. Acute myeloid leukemia (AML-M7) or acute megakaryocytic leukemia is a rare type of AML with an incidence of 0.5 per million per year. Median age of presentation is 6 years, and children may present with a broad variety of symptoms including low-grade fever, diarrhea, easy bruising, failure to gain weight and life-threatening conditions.

摘要

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