先天性急性巨核细胞白血病
Congenital acute megakaryocytic leukemia.
作者信息
Mathur N B, Joshi Neha, Singh T, Singh Meeta
机构信息
Department of Pediatrics, Maulana Azad Medical College, Delhi, India.
出版信息
Indian J Med Paediatr Oncol. 2011 Jul;32(3):165-7. doi: 10.4103/0971-5851.92821.
Congenital leukemia (CL) is an extremely rare disorder in the newborn, significant proportion of which is of myeloid origin, primarily of M4 or M5 morphology. As compared to pediatric leukemia, CL is a more aggressive disease. Acute myeloid leukemia (AML-M7) or acute megakaryocytic leukemia is a rare type of AML with an incidence of 0.5 per million per year. Median age of presentation is 6 years, and children may present with a broad variety of symptoms including low-grade fever, diarrhea, easy bruising, failure to gain weight and life-threatening conditions.
先天性白血病（CL）是新生儿中一种极为罕见的疾病，其中很大一部分起源于髓系，主要为M4或M5形态。与儿童白血病相比，CL是一种侵袭性更强的疾病。急性髓系白血病（AML-M7）或急性巨核细胞白血病是一种罕见的AML类型，年发病率为百万分之0.5。发病的中位年龄为6岁，儿童可能出现多种症状，包括低热、腹泻、易瘀伤、体重不增以及危及生命的情况。
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