Wang Jiang, Zhao Rong
Department of General Surgery, Urumqi General Hospital of Lanzhou Military Region, Urumqi, Xinjiang, 830002, China.
Int J Clin Exp Pathol. 2012;5(3):270-3. Epub 2012 Mar 25.
Gastrointestinal stromal tumors (GISTs) are rare and our understanding of the natural history and optimal treatment of GISTs are continually evolving. They are characterized by a remarkable cellular variability and their malignant potential is sometimes difficult to predict.
We report the case of intestinal stromal tumor in a 44 years old patient with a long history of anemia and recurrent hemafecia. By using (99m)Tc-labeled red blood cell ((99m)Tc-RBC) scintigraphy, extensive tracer accumulation in the jejunum was detected. Immunohistochemically, the tumor strongly expresses the KIT (CD117) protein. The intestinal tumor was successfully resected with a postoperative favorable outcome.
(99m)Tc-RBC scintigraphy is an established technique for the identification and localization of gastrointestinal bleeding. Abdominal scintigraphy appears to be a valuable supplement to conventional diagnostic methods for the diagnosis of gastrointestinal stromal tumor hemorrhage.
胃肠道间质瘤（GISTs）较为罕见，我们对其自然病史和最佳治疗方法的认识在不断发展。它们具有显著的细胞变异性，其恶性潜能有时难以预测。
我们报告一例44岁患有长期贫血和反复便血病史的患者的肠道间质瘤病例。通过使用（99m）锝标记红细胞（（99m）Tc-RBC）闪烁扫描，在空肠中检测到大量示踪剂聚集。免疫组织化学检查显示，肿瘤强烈表达KIT（CD117）蛋白。肠道肿瘤成功切除，术后预后良好。
（99m）Tc-RBC闪烁扫描是一种用于识别和定位胃肠道出血的成熟技术。腹部闪烁扫描似乎是诊断胃肠道间质瘤出血的传统诊断方法的有价值补充。
