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儿科人群中的精神障碍负担。

Burden of psychiatric disorders in the pediatric population.

机构信息

Laboratory for Mother and Child Health, Department of Public Health, Mario Negri Institute for Pharmacological Research, Milan, Italy.

出版信息

Eur Neuropsychopharmacol. 2013 Feb;23(2):98-106. doi: 10.1016/j.euroneuro.2012.04.008. Epub 2012 May 4.

Abstract

In order to estimate the burden of mental disorders in a representative Italian pediatric population, an epidemiological study was performed using three administrative databases: a drug prescription, a hospital discharge form, and an outpatient ambulatory visit database. The population target was 1,616,268 children and adolescents under 18 years living in the Lombardy Region, Italy. A youth was defined as a case if during 2008 he/she received at least one psychotropic drug prescription or was hospitalized for a psychiatric disorder (International Classification of Disease codes 290-319), or attended a child neuropsychiatric outpatient unit for a visit and/or a psychological intervention or rehabilitation at least once. Epileptic children were excluded. In all, 63,550 youths (39.3 per 1000; 95%CI 39.1-39.7‰) were identified as users of health care resources for a putative mental disorder. The prevalence was higher in boys than in girls (47.0‰ versus 31.3‰) and the highest value was recorded in children 8 years old (60.2‰). A total of 59,987 youths (37.1‰) attended a child and adolescent neuropsychiatry service at least once, 3605 (2.2‰) were admitted to hospital, and 2761 (1.7‰) received at least one psychotropic drug prescription, 57% of which did not attend a child neuropsychiatry service. In all, 14,741 youths (23.1% of users) had a disorder that required a high intensity of care (e.g. recurrent prescriptions for drugs and/or ambulatory care). The proportion of youths who received care for mental disorders in the Lombardy Region seems lower than in other countries. However, the fact that many children were prescribed psychotropic drugs without the supervision of a child psychiatrist is a reason for concern.

摘要

为了评估意大利代表性儿科人群中精神障碍的负担,我们使用三个行政数据库开展了一项流行病学研究:药物处方数据库、医院出院表数据库和门诊就诊数据库。目标人群为居住在意大利伦巴第大区的 1616268 名 18 岁以下儿童和青少年。如果 2008 年期间,青少年至少接受过一次精神药物处方或因精神障碍住院(国际疾病分类代码 290-319),或至少一次前往儿童神经精神病门诊就诊和/或接受心理干预或康复治疗,那么将其定义为病例。患有癫痫的儿童被排除在外。共有 63550 名青少年(39.3/1000;95%CI 39.1-39.7‰)被确定为使用医疗资源治疗疑似精神障碍。男孩的患病率高于女孩(47.0‰比 31.3‰),8 岁儿童的患病率最高(60.2‰)。共有 59987 名青少年(37.1‰)至少一次前往儿童和青少年神经精神病科就诊,3605 名(2.2‰)住院,2761 名(1.7‰)接受至少一次精神药物处方,其中 57%的人没有前往儿童神经精神病科就诊。共有 14741 名青少年(占使用者的 23.1%)患有需要高强度护理的疾病(例如药物的重复处方和/或门诊护理)。伦巴第大区接受精神障碍治疗的青少年比例似乎低于其他国家。然而,许多儿童在没有儿童精神科医生监督的情况下接受精神药物治疗这一事实令人担忧。

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