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弗吉尼亚州汉普顿路非西班牙裔黑人和白人人群中的婴儿死亡流行病学。

Epidemiology of infant death among black and white non-Hispanic populations in Hampton Roads, Virginia.

作者信息

Emuren Leonard, Chauhan Suneet, Vroman Richard, Beydoun Hind

机构信息

From the Graduate Program in Public Health and the Department of Obstetrics and Gynecology, Eastern Virginia Medical School, Norfolk 23501-1980, USA.

出版信息

South Med J. 2012 May;105(5):259-65. doi: 10.1097/SMJ.0b013e3182541676.

Abstract

OBJECTIVE

To evaluate the presence of racial disparities in infant mortality rates and assess risk factors for infant death among black and white populations in Hampton Roads, Virginia.

METHODS

A retrospective study with secondary analyses of linked birth/death certificate data was conducted using a sample of 201,610 live-born infants and 1659 infant deaths identified between January 1, 1999 and December 31, 2008 in Hampton Roads.

RESULTS

Infant, neonatal, and postneonatal mortality rates were significantly (P < 0.0001) higher among black compared with white populations. Racial disparities were noted whereby black infants were significantly (P < 0.0001) more likely to die of conditions originating in the perinatal period, whereas white infants were significantly more likely to die of congenital malformations, deformations, and chromosomal abnormalities (P < 0.0001) or neoplasms (P = 0.03). Multivariable logistic modeling suggested significantly higher odds of black infants dying in the first year of life than white infants. Among blacks, the odds of infant death were inversely related to maternal education. Among whites, the odds of infant death declined with increasing parity. Among black and white populations, history of child death, presence of maternal morbidities and the Kotelchuck Maternal Utilization of Prenatal Care Index were key determinants of infant death.

CONCLUSIONS

Black infants are at higher odds of dying compared with white infants in Hampton Roads, Virginia. Continued efforts should target prenatal care, preterm delivery, and low-birth-weight infants and neonates to reduce infant mortality rates.

摘要

目的

评估弗吉尼亚州汉普顿路地区婴儿死亡率的种族差异,并评估黑人和白人人群中婴儿死亡的风险因素。

方法

采用回顾性研究方法,对1999年1月1日至2008年12月31日期间在汉普顿路地区出生的201,610名活产婴儿和1,659例婴儿死亡病例的出生/死亡证明数据进行二次分析。

结果

黑人婴儿的婴儿、新生儿和新生儿后期死亡率显著高于白人(P < 0.0001)。种族差异表现为黑人婴儿死于围产期疾病的可能性显著更高(P < 0.0001),而白人婴儿死于先天性畸形、变形和染色体异常(P < 0.0001)或肿瘤(P = 0.03)的可能性显著更高。多变量逻辑模型显示,黑人婴儿在生命第一年死亡的几率显著高于白人婴儿。在黑人中,婴儿死亡几率与母亲教育程度呈负相关。在白人中,婴儿死亡几率随着产次增加而下降。在黑人和白人人群中,儿童死亡史、母亲发病情况以及科特尔丘克产前保健利用指数是婴儿死亡的关键决定因素。

结论

在弗吉尼亚州汉普顿路地区,黑人婴儿死亡的几率高于白人婴儿。应继续针对产前护理、早产以及低体重婴儿和新生儿采取措施,以降低婴儿死亡率。

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