主动脉瓣硬化是冠状动脉疾病的一个指标。

Aortic valve sclerosis is an indicator of coronary artery diseases.

作者信息

Roy G C, Rahman F, Hoque M H, Habib M A, Banerjee S K, Siddique M A, Barua U K, Hossain A S, Bhuiyan G R, Haider M S

机构信息

Department of Medicine, Mymensingh Medical College, Mymensingh, Bangladesh.

出版信息

Mymensingh Med J. 2012 Apr;21(2):226-32.

PMID:22561763

Abstract

Aim of this study is to establish the relationship between echocardiographically detected Aortic Valve Sclerosis (AVS) and angiographically detected Coronary Artery Diseases (CAD). This observational and cross-sectional study was carried out in the department of cardiology BSMMU, Dhaka from January 2010 to November 2010. A total 140 patients of established or suspected coronary artery disease admitted for coronary angiogram was included in this study. Echocardiography and coronary angiography was done. AVS was found in 88(63%) patients. With AVS 81(92.05%) had significant coronary artery disease. Fifty two patients without AVS, 42(80%) had significant coronary artery disease. No significant difference of SVD in both groups but patients with AVS had a higher rate of DVD, TVD and LM disease. Patients without AVS had a higher rate of normal coronary angiogram. Multivariate analysis identified AVS (p=0.018) is an independent predictor of CAD.

摘要

本研究的目的是建立超声心动图检测到的主动脉瓣硬化（AVS）与血管造影检测到的冠状动脉疾病（CAD）之间的关系。这项观察性横断面研究于2010年1月至2010年11月在达卡BSMMU心脏病学系进行。本研究纳入了总共140例因冠状动脉造影而入院的确诊或疑似冠状动脉疾病患者。进行了超声心动图和冠状动脉造影检查。88例（63%）患者发现有AVS。有AVS的患者中，81例（92.05%）患有严重冠状动脉疾病。52例无AVS的患者中，42例（80%）患有严重冠状动脉疾病。两组患者的单支血管病变（SVD）无显著差异，但有AVS的患者双支血管病变（DVD）、三支血管病变（TVD）和左主干病变（LM disease）的发生率较高。无AVS的患者冠状动脉造影正常的发生率较高。多因素分析确定AVS（p=0.018）是CAD的独立预测因素。