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老年人大肠癌及腺瘤的早期诊断与治疗中的问题

[Problems in the early diagnosis and treatment of colorectal carcinoma and adenoma in the aged].

作者信息

Zoubek V, Zoubková H, Mrůzek M

机构信息

Okresní ústav národního zdraví, Bruntál.

出版信息

Vnitr Lek. 1990 Oct;36(10):998-1001.

PMID:2256262
Abstract

In 1985-1989 in the Bruntál district by means of the test for occult haemorrhage (Haemoccult, Röhm Pharma Co.) a total of 1084 subjects aged 65-86 years were examined. The test was positive in 74 subjects (6.83%). A subsequent coloscopic examination was made in 60 subjects, 81% of those with a positive test. Coloscopic examination revealed 8 patients with carcinoma of the large intestine and 45 patients with an adenomatous polyp. The oncological positivity is thus 4.89% of the tested subjects and 88.33% of those subjected to coloscopy. The carcinoma was evaluated in two cases in the stage Dukes A, in four instances in stage Dukes B, in one case in stage Dukes C and in one case in stage Dukes D. In two patients with carcinoma another adenomatous polyp was found in the large intestine. In 14 patients of 45 with an adenomatous polyp another synchronous adenomatous polyp was detected (31.1%). 43 patients were treated by coloscopic polypectomy. Contemporary possibilities of early diagnosis of colorectal carcinoma in conjunction with effective therapeutic endoscopy are perspective in particular in patients of advanced age.

摘要

1985年至1989年期间,在布伦塔尔地区,借助潜血检测(海莫克检测,罗姆制药公司)对1084名年龄在65至86岁之间的受试者进行了检查。检测呈阳性的有74名受试者(6.83%)。随后对60名受试者进行了结肠镜检查,占检测呈阳性者的81%。结肠镜检查发现8例患有大肠癌,45例患有腺瘤性息肉。因此,肿瘤阳性率在受检者中为4.89%,在接受结肠镜检查者中为88.33%。对2例癌症患者评估为杜克A期,4例为杜克B期,1例为杜克C期,1例为杜克D期。在2例癌症患者的大肠中还发现了另一个腺瘤性息肉。在45例患有腺瘤性息肉的患者中,有14例检测到另一个同步腺瘤性息肉(31.1%)。43例患者接受了结肠镜息肉切除术。结合有效的治疗性内镜检查,大肠癌早期诊断的当代可能性尤其在老年患者中具有前景。

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