• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Esterase profile of O-phosphorylated ethyltrifluorolactates in prediction of their therapeutic and toxic effects.

作者信息

Rudakova E V, Makhaeva G F, Galenko T G, Aksinenko A Yu, Sokolov V B, Richardson R J, Martynov I V

机构信息

Institute of Physiologically Active Compounds, Russian Academy of Sciences, Severny pr. 1, Chernogolovka, Moscow oblast, 142432 Russia.

出版信息

Dokl Biochem Biophys. 2012 Mar-Apr;443:81-5. doi: 10.1134/S1607672912020068. Epub 2012 May 5.

DOI:10.1134/S1607672912020068
PMID:22562631
Abstract
摘要

相似文献

1
Esterase profile of O-phosphorylated ethyltrifluorolactates in prediction of their therapeutic and toxic effects.
Dokl Biochem Biophys. 2012 Mar-Apr;443:81-5. doi: 10.1134/S1607672912020068. Epub 2012 May 5.
2
Organophosphorus compound esterase profiles as predictors of therapeutic and toxic effects.有机磷化合物酯酶谱作为治疗和毒性效应的预测指标。
Chem Biol Interact. 2013 Mar 25;203(1):231-7. doi: 10.1016/j.cbi.2012.10.012. Epub 2012 Nov 2.
3
[Specific interaction between esterases and 2-butylthio-2-thio-1,3,2-oxazaphosphorynane and its cyclic and acyclic analogs].[酯酶与2-丁硫基-2-硫代-1,3,2-氧氮磷杂环戊烷及其环状和非环状类似物之间的特异性相互作用]
Izv Akad Nauk Ser Biol. 2002 Jan-Feb(1):93-101.
4
Esterase profile and analysis of structure-inhibitor selectivity relationships for homologous phosphorylated 1-hydroperfluoroisopropanols.同源磷酸化1-氢全氟异丙醇的酯酶谱及结构-抑制剂选择性关系分析
Dokl Biochem Biophys. 2008 Nov-Dec;423:352-7. doi: 10.1134/s1607672908060094.
5
Comparison of inhibitory activity of various organophosphorus compounds against acetylcholinesterase and neurotoxic esterase of hens with respect to delayed neurotoxicity.各种有机磷化合物对母鸡乙酰胆碱酯酶和神经毒性酯酶的抑制活性与迟发性神经毒性的比较。
Biochem Pharmacol. 1980 Oct 15;29(20):2721-7. doi: 10.1016/0006-2952(80)90002-7.
6
Irreversible phosphorylation of brain neurotoxic esterase. The primary event leading to the delayed neuropathy caused by some organophosphorus esters.脑神经毒性酯酶的不可逆磷酸化。这是导致某些有机磷酸酯引起迟发性神经病的主要事件。
Monogr Neural Sci. 1980;7:99-105.
7
Nature of the reaction of organophosphorus compounds and carbamates with esterases.有机磷化合物和氨基甲酸酯与酯酶的反应性质。
Hoppe Seylers Z Physiol Chem. 1973 Jan;354(1):4-5.
8
A comparative study of antichymotryptic and anticholinesterase activity of organophosphorus quasi-substrate inhibitors.有机磷类准底物抑制剂的抗胰凝乳蛋白酶和抗胆碱酯酶活性的比较研究。
Dokl Biochem Biophys. 2008 Mar-Apr;419:82-7. doi: 10.1134/s1607672908020105.
9
Inhibition with spontaneous reactivation and the "ongoing inhibition" effect of esterases by biotinylated organophosphorus compounds: S9B as a model.生物素化有机磷化合物对酯酶的自发复能抑制和“持续抑制”效应：以 S9B 为模型。
Chem Biol Interact. 2010 Sep 6;187(1-3):397-402. doi: 10.1016/j.cbi.2010.05.008. Epub 2010 May 20.
10
The primary biochemical lesion leading to the delayed neurotoxic effects of some organophosphorus esters.导致某些有机磷酸酯延迟神经毒性作用的主要生化损伤。
J Neurochem. 1974 Oct;23(4):785-9. doi: 10.1111/j.1471-4159.1974.tb04404.x.

引用本文的文献

1
N,N-disubstituted 2-aminothiazolines as new inhibitors of serine esterases.
Dokl Biochem Biophys. 2013 Jul-Aug;451:209-11. doi: 10.1134/S160767291304011X. Epub 2013 Aug 23.

本文引用的文献

1
Synthesis of organophosphates with fluorine-containing leaving groups as serine esterase inhibitors with potential for Alzheimer disease therapeutics.含氟离去基团的有机磷酸酯作为丝氨酸酯酶抑制剂的合成及其在阿尔茨海默病治疗中的潜力。
Bioorg Med Chem Lett. 2009 Oct 1;19(19):5528-30. doi: 10.1016/j.bmcl.2009.08.065. Epub 2009 Aug 21.
2
Esterase profile and analysis of structure-inhibitor selectivity relationships for homologous phosphorylated 1-hydroperfluoroisopropanols.同源磷酸化1-氢全氟异丙醇的酯酶谱及结构-抑制剂选择性关系分析
Dokl Biochem Biophys. 2008 Nov-Dec;423:352-7. doi: 10.1134/s1607672908060094.
3
Selective butyrylcholinesterase inhibition elevates brain acetylcholine, augments learning and lowers Alzheimer beta-amyloid peptide in rodent.
选择性丁酰胆碱酯酶抑制可提高啮齿动物大脑中的乙酰胆碱水平，增强学习能力并降低β-淀粉样肽。
Proc Natl Acad Sci U S A. 2005 Nov 22;102(47):17213-8. doi: 10.1073/pnas.0508575102. Epub 2005 Nov 7.
4
Cholinesterase inhibitors: new roles and therapeutic alternatives.胆碱酯酶抑制剂：新作用及治疗选择
Pharmacol Res. 2004 Oct;50(4):433-40. doi: 10.1016/j.phrs.2003.11.017.
5
Quantitative structure-activity relationships predict the delayed neurotoxicity potential of a series of O-alkyl-O-methylchloroformimino phenylphosphonates.定量构效关系预测了一系列O-烷基-O-甲基氯亚氨基苯基膦酸酯的迟发性神经毒性潜力。
J Toxicol Environ Health A. 2003 Apr 11;66(7):611-25. doi: 10.1080/15287390309353770.
6
A stable preparation of hen brain neuropathy target esterase for rapid biochemical assessment of neurotoxic potential of organophosphates.
Chem Biol Interact. 1999 May 14;119-120:551-7. doi: 10.1016/s0009-2797(99)00069-1.
7
Comparative studies of O,O-dialkyl-O-chloromethylchloroformimino phosphates: interaction with neuropathy target esterase and acetylcholinesterase.O,O-二烷基-O-氯甲基氯代甲亚胺基磷酸酯的比较研究：与神经病变靶酯酶和乙酰胆碱酯酶的相互作用
Neurotoxicology. 1998 Aug-Oct;19(4-5):623-8.
8
[Interaction of dialkyl(alpha-carbomethoxy-beta,beta,beta-trifluoro- ethyl) phosphates with mammalian esterases].
Bioorg Khim. 1987 Jan;13(1):33-7.