Department of Biological Engineering, University of Missouri, Columbia, MO 65211, USA.
Physiol Meas. 2012 Jun;33(6):1043-52. doi: 10.1088/0967-3334/33/6/1043. Epub 2012 May 4.
We investigated the potential inter-relationship between two measures of autonomic nervous system: pupillary light reflex (PLR) and heart rate variability (HRV), in healthy children of 8-16 years old. PLR was measured at both dark- and light-adapted conditions with various stimulation intensities. Simultaneously measured HRV was obtained in five different PLR testing phases: before PLR test, light-adapted PLR test, dark adaptation, dark-adapted PLR test and after PLR test. The frequency domain HRV parameters measured during the PLR test were significantly different from those measured during rest. Both the regression analysis and factor analysis indicated that PLR and HRV parameters were not correlated, which suggests that they may provide complementary assessment of different aspects of the overall autonomic nervous system.
我们研究了 8-16 岁健康儿童的两种自主神经系统测量指标——瞳孔对光反射（PLR）和心率变异性（HRV）之间的潜在相互关系。PLR 在暗适应和明适应条件下分别用不同的刺激强度进行测量。同时在五个不同的 PLR 测试阶段测量 HRV：PLR 测试前、明适应 PLR 测试、暗适应、暗适应 PLR 测试和 PLR 测试后。PLR 测试过程中测量的频域 HRV 参数与休息时测量的参数有显著差异。回归分析和因子分析都表明，PLR 和 HRV 参数不相关，这表明它们可能提供了对整体自主神经系统不同方面的补充评估。
