Improving standards in brain-behavior correlation analyses.

Associations between two variables, for instance between brain and behavioral measurements, are often studied using correlations, and in particular Pearson correlation. However, Pearson correlation is not robust: outliers can introduce false correlations or mask existing ones. These problems are exacerbated in brain imaging by a widespread lack of control for multiple comparisons, and several issues with data interpretations. We illustrate these important problems associated with brain-behavior correlations, drawing examples from published articles. We make several propositions to alleviate these problems.