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稳健相关性分析:使用新的开源 MATLAB 工具箱进行假阳性和功效验证。

Robust correlation analyses: false positive and power validation using a new open source matlab toolbox.

机构信息

Brain Research Imaging Center, Division of Clinical Neurosciences, University of Edinburgh Edinburgh, UK.

出版信息

Front Psychol. 2013 Jan 10;3:606. doi: 10.3389/fpsyg.2012.00606. eCollection 2012.

Abstract

Pearson's correlation measures the strength of the association between two variables. The technique is, however, restricted to linear associations and is overly sensitive to outliers. Indeed, a single outlier can result in a highly inaccurate summary of the data. Yet, it remains the most commonly used measure of association in psychology research. Here we describe a free Matlab((R)) based toolbox (http://sourceforge.net/projects/robustcorrtool/) that computes robust measures of association between two or more random variables: the percentage-bend correlation and skipped-correlations. After illustrating how to use the toolbox, we show that robust methods, where outliers are down weighted or removed and accounted for in significance testing, provide better estimates of the true association with accurate false positive control and without loss of power. The different correlation methods were tested with normal data and normal data contaminated with marginal or bivariate outliers. We report estimates of effect size, false positive rate and power, and advise on which technique to use depending on the data at hand.

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d4f/3541537/3d007a622ca9/fpsyg-03-00606-g001.jpg

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