Grando S A, Glukhen'kiĭ B T, Stupina A S, Terman A K
Vestn Dermatol Venerol. 1990(8):11-4.
Analysis of the results of light optic, immunofluorescent, and electron microscopic studies of biopsy specimens of intact skin of forearms and of the skin adjacent to lesions in 10 patients with untreated pemphigus vulgaris has lead the authors to a conclusion on the uniform pattern of ultrastructural changes in all sites of the epidermis in pemphigus patients. A combination of the signs of involvement of prickle and basal-cell structures (desmosomes and mitochondria) and of signs of cellular metabolic activation (euchromatism, active status of the nucleolus) anticipate the development of intra- and extracellular changes in pemphigus.
对10例未经治疗的寻常型天疱疮患者前臂完整皮肤及皮损周边皮肤活检标本进行光学、免疫荧光及电子显微镜研究，结果使作者得出结论：天疱疮患者表皮所有部位的超微结构变化模式一致。棘层和基底细胞结构（桥粒和线粒体）受累的迹象与细胞代谢激活的迹象（核染色质浅色化、核仁活跃状态）相结合，预示着天疱疮患者细胞内和细胞外变化的发展。
