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[梅毒早期阶段梅毒螺旋体特异性血液免疫球蛋白的动态变化]

[The dynamics of Treponema-specific blood immunoglobulins in early forms of syphilis].

作者信息

Liakhov V F, Borisenko K K, Potekaev N S, Borisova T K, Sidorova E V

出版信息

Vestn Dermatol Venerol. 1990(8):38-42.

PMID:2256377
Abstract

The study has involved 73 patients with syphilis, 31 female and 42 male ones, aged 18-42. Four of these suffered from primary seronegative, 14 from primary seropositive, 21 from secondary fresh, 22 from secondary recurrent, and 12 from early latent seropositive syphilis. Peripheral blood sera were under study. Treponema-specific antibodies of the IgM and IgG classes were titered by enzyme immunoassay. The detected changes in Treponema-specific immunoglobulinemia are in good correlation with clinical staged pattern of syphilis and antiinfectious immunity status.

摘要

该研究纳入了73例梅毒患者,其中女性31例,男性42例,年龄在18至42岁之间。这些患者中,4例为一期血清阴性梅毒,14例为一期血清阳性梅毒,21例为二期早期梅毒,22例为二期复发梅毒,12例为早期潜伏血清阳性梅毒。研究对象为外周血血清。采用酶免疫测定法对IgM和IgG类梅毒螺旋体特异性抗体进行滴定。检测到的梅毒螺旋体特异性免疫球蛋白血症变化与梅毒的临床分期模式和抗感染免疫状态密切相关。

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