Institute of Cancer Epidemiology, University of Lübeck, Ratzeburger Allee 160, 23538 Lübeck, Germany.
Br J Dermatol. 2012 Sep;167(3):606-12. doi: 10.1111/j.1365-2133.2012.11039.x. Epub 2012 Jul 19.
Prior analyses of survival of patients with primary cutaneous malignant melanoma from Germany were based only on small populations and need to be updated.
We give a detailed overview of relative 5-year survival by sex, age group, histology, tumour stage and body site, and of time trends in a population of 33 million (40% of Germany), and compare survival in the federal states.
Conventional and model-based period analysis using the Ederer II method was applied to patients with melanoma diagnosed during 1997-2006 in Germany to assess 5-year relative survival (RS) rates and time trends.
In total, 37,155 melanoma cases were included. Overall age-adjusted 5-year RS for the time period 2002-2006 was 91·9% for women and 87·0% for men. Survival differences by age group, histology, tumour stage and body site were found. No significant overall trend (2002-2006) was seen either in women or in men. Differences in survival between federal states were small; no clear pattern was seen.
Based on the most recent and high-quality data from population-based cancer registries a comprehensive picture on melanoma survival in Germany was given. Survival from cutaneous malignant melanoma was high compared with other cancer sites and did not change during the analysed period 2002-2006. Patterns in melanoma survival by sex, age, tumour stage, histology and body site were in good agreement with previously published findings. No relevant differences between federal states were found.
先前对德国原发性皮肤恶性黑素瘤患者生存情况的分析仅基于小样本人群，因此需要更新。
我们详细概述了 3300 万人群（占德国人口的 40%）中按性别、年龄组、组织学、肿瘤分期和部位划分的相对 5 年生存率，并比较了各联邦州的生存率。
采用 Ederer II 法的常规和基于模型的时期分析，应用于德国 1997-2006 年间诊断的黑素瘤患者，以评估 5 年相对生存率（RS）率和时间趋势。
共纳入 37155 例黑素瘤病例。2002-2006 年期间，年龄校正后的总 5 年 RS 为女性 91.9%，男性 87.0%。按年龄组、组织学、肿瘤分期和部位划分，生存率存在差异。女性或男性均未观察到总体趋势（2002-2006 年）有显著变化。各联邦州之间的生存率差异较小，没有明显的模式。
基于基于人群的癌症登记处的最新和高质量数据，给出了德国黑素瘤生存情况的综合情况。与其他癌症部位相比，皮肤恶性黑素瘤的生存率较高，在 2002-2006 年分析期间没有变化。按性别、年龄、肿瘤分期、组织学和部位划分的黑素瘤生存率模式与先前发表的研究结果一致。未发现各联邦州之间存在显著差异。
