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Platelet factor 4 platelet levels are inversely correlated with steady-state platelet counts and with platelet transfusion needs in pediatric leukemia patients.

作者信息

Lambert M P, Reznikov A, Grubbs A, Nguyen Y, Xiao L, Aplenc R, Rauova L, Poncz M

出版信息

J Thromb Haemost. 2012 Jul;10(7):1442-6. doi: 10.1111/j.1538-7836.2012.04767.x.

DOI:10.1111/j.1538-7836.2012.04767.x
PMID:22564375
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3389572/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7bca/3389572/53844f77596e/nihms-375615-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7bca/3389572/53844f77596e/nihms-375615-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7bca/3389572/53844f77596e/nihms-375615-f0001.jpg

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本文引用的文献

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The role of platelet factor 4 in radiation-induced thrombocytopenia.血小板因子 4 在放射性诱导血小板减少症中的作用。
Int J Radiat Oncol Biol Phys. 2011 Aug 1;80(5):1533-40. doi: 10.1016/j.ijrobp.2011.03.039.
2
Intensively timed combination chemotherapy for the induction of adult patients with acute myeloid leukemia: long-term follow-up of a phase 2 study.强化计时联合化疗诱导成人急性髓系白血病：一项 2 期研究的长期随访。
Cancer. 2010 Nov 15;116(22):5272-8. doi: 10.1002/cncr.25516.
3
Platelet factor 4 regulates megakaryopoiesis through low-density lipoprotein receptor-related protein 1 (LRP1) on megakaryocytes.血小板第4因子通过巨核细胞上的低密度脂蛋白受体相关蛋白1（LRP1）调节巨核细胞生成。
Blood. 2009 Sep 10;114(11):2290-8. doi: 10.1182/blood-2009-04-216473. Epub 2009 Jul 15.
4
Management of chemotherapy-induced thrombocytopenia: current status of thrombopoietic agents.化疗诱导的血小板减少症的管理：血小板生成药物的现状
Semin Hematol. 2009 Jan;46(1 Suppl 2):S26-32. doi: 10.1053/j.seminhematol.2008.12.007.
5
Platelet factor 4 is a negative autocrine in vivo regulator of megakaryopoiesis: clinical and therapeutic implications.血小板因子4是体内巨核细胞生成的负性自分泌调节因子：临床及治疗意义
Blood. 2007 Aug 15;110(4):1153-60. doi: 10.1182/blood-2007-01-067116. Epub 2007 May 10.
6
Recombinant human thrombopoietin: basic biology and evaluation of clinical studies.重组人血小板生成素：基础生物学及临床研究评估
Blood. 2002 Nov 15;100(10):3457-69. doi: 10.1182/blood.V100.10.3457.
7
Incidence, cost, and outcomes of bleeding and chemotherapy dose modification among solid tumor patients with chemotherapy-induced thrombocytopenia.实体瘤化疗所致血小板减少症患者出血、化疗剂量调整的发生率、成本及结局
J Clin Oncol. 2001 Feb 15;19(4):1137-46. doi: 10.1200/JCO.2001.19.4.1137.
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Granulocyte colony stimulating factor permits dose intensification by interval compression in the treatment of Ewing's sarcomas and soft tissue sarcomas in children.粒细胞集落刺激因子可通过缩短疗程间隔来增加剂量强度，用于治疗儿童尤因肉瘤和软组织肉瘤。
Eur J Cancer. 2000 Jan;36(1):87-94. doi: 10.1016/s0959-8049(99)00236-1.
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