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器官分配政策对患者接受心脏移植的几率及移植后生存率的影响。

The influence of the organ allocation policy on a patient's chances of undergoing heart transplantation and the posttransplantation survival rate.

作者信息

Tsao C-I, Chou N-K, Chi N-H, Chen S-C, Ko W-J, Yu H-Y, Chen Y-S, Wang S-S

机构信息

Department of Nursing, National Taiwan University Hospital, Taipei, Taiwan.

出版信息

Transplant Proc. 2012 May;44(4):881-2. doi: 10.1016/j.transproceed.2012.03.025.

DOI:10.1016/j.transproceed.2012.03.025
PMID:22564573
Abstract

The Taiwan Organ Registry and Sharing Center (TORSC) was established by the Department of Health on June 6, 2002. According to the organ allocation policy, the computer-based organ-matching program began on April 1, 2005. In order to encourage organ donations, "donor hospitals" were given the highest priority. On October 1, 2010, the TORSC implemented a new allocation policy allowing highest priority to the most critically ill patients listed as 1A status. The aim of this study was to investigate the influence of the allocation policy on the likelihood of undergoing a heart transplantation (HTx) as well as the survival after the procedure. Based on the timeline of changes in the organ allocation policy, the patients were divided into three groups: "individual decision," "donor hospital first," and "urgency status first." We observed the waiting time of status 1A patients to decrease and their chance to receive a donor heart increase but their survival rate after HTx to decrease. Further research is needed to define the optimal organ allocation policy.

摘要

台湾器官移植登记及共享中心(TORSC)于2002年6月6日由台湾地区卫生署设立。根据器官分配政策,基于计算机的器官匹配程序于2005年4月1日启动。为鼓励器官捐赠,“捐赠医院”被给予最高优先级。2010年10月1日,TORSC实施了一项新的分配政策,将最高优先级给予列为1A状态的最危重患者。本研究的目的是调查分配政策对接受心脏移植(HTx)可能性以及术后生存情况的影响。根据器官分配政策变化的时间线,患者被分为三组:“个人决定”组、“捐赠医院优先”组和“紧急状态优先”组。我们观察到1A状态患者的等待时间缩短,接受供体心脏的机会增加,但HTx术后的生存率下降。需要进一步研究来确定最佳的器官分配政策。

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