Department of Pediatrics, University of Colorado Denver, Aurora, Colorado, 80045, USA.
Pediatrics. 2012 Jun;129(6):e1446-52. doi: 10.1542/peds.2011-2921. Epub 2012 May 7.
Effectiveness of recall for immunizations has not been examined in the setting of school-based health centers (SBHCs). We assessed (1) immunization rates achieved with recall among sixth-grade girls (demonstration study); (2) effectiveness of recall among sixth-grade boys (randomized controlled trial [RCT]); and (3) cost of conducting recall in SBHCs.
During October 2008 through March 2009, in 4 Denver public SBHCs, we conducted (1) a demonstration study among 265 girls needing ≥ 1 recommended adolescent vaccine and (2) an RCT among 264 boys needing vaccines, with half randomized to recall and half receiving usual care. Immunization rates for recommended adolescent vaccines were assessed 6 months after recall. First dose costs were assessed by direct observation and examining invoices.
At the end of the demonstration study, 77% of girls had received ≥ 1 vaccine and 45% had received all needed adolescent vaccines. Rates of receipt among those needing each of the vaccines were 68% (160/236) for tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine, 57% (142/248) for quadrivalent meningococcal conjugate vaccine, and 59% (149/253) for the first human papillomavirus vaccine. At the end of the RCT, 66% of recalled boys had received ≥ 1 vaccine and 59% had received all study vaccines, compared with 45% and 36%, respectively, of the control group (P < .001). Cost of conducting recall ranged from $1.12 to $6.87 per recalled child immunized.
SBHC-based recall was effective in improving immunization rates for all adolescent vaccines, with effects sizes exceeding those achieved with younger children in practice settings.
在学校卫生中心(SBHC)环境中,尚未对免疫接种的召回效果进行检查。我们评估了(1)通过召回方式实现的六年级女生(示范研究)的免疫接种率;(2)六年级男生(随机对照试验 [RCT])的召回效果;(3)在 SBHC 进行召回的成本。
在 2008 年 10 月至 2009 年 3 月期间,在丹佛的 4 所公立 SBHC 中,我们进行了(1)对 265 名需要≥1 种推荐青少年疫苗的女生的示范研究,以及(2)对 264 名需要疫苗的男生的 RCT,其中一半随机进行召回,另一半接受常规护理。在召回后 6 个月评估推荐的青少年疫苗接种率。通过直接观察和检查发票评估第一剂成本。
在示范研究结束时,77%的女生接种了≥1 种疫苗,45%的女生接种了所有需要的青少年疫苗。需要每种疫苗的女生接种率分别为破伤风类毒素、白喉类毒素和无细胞百日咳疫苗 68%(236/346)、四价脑膜炎球菌结合疫苗 57%(248/434)和人乳头瘤病毒疫苗第一剂 59%(253/431)。在 RCT 结束时,66%的召回男孩接种了≥1 种疫苗,59%的男孩接种了所有研究疫苗,而对照组分别为 45%和 36%(P<0.001)。进行召回的成本范围为每例被召回儿童免疫接种 1.12 美元至 6.87 美元。
基于 SBHC 的召回在提高所有青少年疫苗的免疫接种率方面是有效的,其效果大小超过了在实践环境中对年幼儿童的效果。