Fondazione Don Carlo Gnocchi, Scientific Institute, Outpatient Rehabilitation Department, Florence, Italy.
Eur J Phys Rehabil Med. 2012 Sep;48(3):371-8. Epub 2012 May 8.
Recent studies on chronic low back pain (cLBP) rehabilitation suggest that predictors of treatment outcome may be differ according to the considered conservative treatment.
To identify predictors of response to back school (BS), individual physiotherapy (IP) or spinal manipulation (SM) for cLBP.
outpatients with cLBP.
Outpatient rehabilitation department.
Retrospective analysis from a randomized trial.
Two hundred and ten patients with cLBP were randomly assigned to either BS, IP or SM; the Roland Morris Disability Questionnaire (RM) was assessed before and after treatment: those who decreased their RM score <2.5 were considered non-responders. Baseline potential predictors of outcome included demographics, general and cLBP history, life satisfaction.
Of the 205 patients who completed treatment (140/205 women, age 58+14 years), non-responders were 72 (34.2%). SM showed the highest functional improvement and the lowest non-response rate. In a multivariable logistic regression, lower baseline RM score (OR 0.82, 95% CI 0.76-0.89, P<0.001) and received treatment (OR 0.32, 95% CI 0.21-0.50, P<0.001) were independent predictors of non-response. Being in the lowest tertile of baseline RM score (<6) predicted non response to treatment for BS and IP, but not for SM (same risk for all tertiles).
In our patients with cLBP lower baseline pain-related disability predicted non-response to physiotherapy, but not to spinal manipulation.
Our results suggest that, independent form other characteristics, patients with cLBP and low pain-related disability should first consider spinal manipulation as a conservative treatment.
最近关于慢性下腰痛(cLBP)康复的研究表明,治疗结果的预测因素可能因所考虑的保守治疗方法而异。
确定背校(BS)、个体物理治疗(IP)或脊柱手法治疗(SM)治疗 cLBP 的反应预测因素。
慢性下腰痛患者。
门诊康复科。
一项随机试验的回顾性分析。
210 例慢性下腰痛患者被随机分配至 BS、IP 或 SM 组;治疗前后采用 Roland Morris 残疾问卷(RM)进行评估:RM 评分下降<2.5 者视为无反应者。基线潜在结局预测因素包括人口统计学、一般和 cLBP 病史、生活满意度。
205 例完成治疗的患者(140/205 例女性,年龄 58+14 岁)中,72 例(34.2%)为无反应者。SM 显示出最高的功能改善和最低的无反应率。多变量逻辑回归分析显示,基线 RM 评分较低(OR 0.82,95%CI 0.76-0.89,P<0.001)和接受治疗(OR 0.32,95%CI 0.21-0.50,P<0.001)是无反应的独立预测因素。基线 RM 评分最低三分位(<6)预测 BS 和 IP 治疗无反应,但对 SM 无预测作用(所有三分位风险相同)。
在我们的慢性下腰痛患者中,较低的基线疼痛相关残疾预测对物理治疗无反应,但对脊柱手法治疗无反应。
我们的研究结果表明,无论其他特征如何,疼痛相关残疾程度较低的慢性下腰痛患者应首先考虑脊柱手法治疗作为保守治疗方法。