Department for Gynecology and Obstetrics, University of Schleswig-Holstein, Campus Luebeck, Ratzeburgerallee 160, 23538, Lübeck, Germany.
Arch Gynecol Obstet. 2012 Sep;286(3):633-6. doi: 10.1007/s00404-012-2334-2. Epub 2012 May 9.
Oxytocin donation in caesarean section is used to reduce postpartum blood loss. Cardiovascular side effects such as tachycardia, hypotension and decreased cardiac output are known and seem to depend on the way of application, whereas the blood loss is said to be similar. We aimed to examine that extent of haemorrhage in our own patients.
In July 2011, the perioperative oxytocin management was changed and the postpartum was oxytocin bolus abolished. Retrospectively, we reviewed the pre- and postpartum haemoglobin in all women who had undergone caesarean section in the year 2011 at the University Hospital of Schleswig-Holstein, Campus Luebeck.
We found a significantly higher blood loss in those patients who were treated without oxytocin bolus but only with oxytocin infusion (-10.5 vs. -9 g/dl).
We recommend to do further studies to clarify the advantage and contraindications of using oxytocin boluses and until to use the oxytocin bolus again in healthy patients but to avoid it in patients with cardiovascular risk.
剖宫产时使用催产素捐献可减少产后出血。已知心血管副作用，如心动过速、低血压和心输出量降低，这些副作用似乎取决于应用方式，而出血量则相似。我们旨在检查我们自己患者的出血程度。
2011 年 7 月，改变了围手术期催产素管理方式，产后催产素推注被取消。回顾性地，我们在 2011 年，吕贝克大学医院院区对所有行剖宫产术的女性进行了术前和术后血红蛋白检查。
我们发现，不使用催产素推注，仅使用催产素输注的患者失血明显更多（-10.5 比-9g/dl）。
我们建议进一步研究，以阐明使用催产素推注的优势和禁忌，并在健康患者中再次使用催产素推注，但避免在心血管风险患者中使用。
