Carvalho Iara Ribeiro, Loscalzo Izabella Tesoto, Freitas Mayteé Fernandes Borges de, Jordão Regina Esteves, Friano Tatiane de Cássia
Department of Food and Nutrition at the University of Campinas, Campinas, SP, Brazil.
Arq Bras Cir Dig. 2012 Jan-Mar;25(1):36-40. doi: 10.1590/s0102-67202012000100009.
Patients undergoing bariatric surgery may develop over time, some complications and anemia is an important one due to gastric resection, leading to iron, folic acid or vitamin B12 deficiency.
To determine the incidence of deficiency of vitamin B12 and other anthropometric and biochemical data comparing the preoperative and postoperative (six months) period in patients who underwent bariatric surgery with Fobi-Capella (Roux-en-Y) technique.
Retrospective and descriptive analysis of 91 charts of patients who underwent surgery. It was collected personal information, date of surgery and pre-and postoperative (six months) values, weight loss, comorbidities, serum analysis of total cholesterol, triglycerides, glucose, vitamin B12, hemoglobin and hematocrit. For statistical analysis, it was considered significance level of 5% (p<0.05).
It was found that there was a reduction in weight of 25,0% compared with the preoperative value and the average BMI was from 41,2±4,9 kg/m² to 30,7±3,9 kg/m². The most common co-morbidities were dyspnea (93,4%), spine alterations (61,5%), gastroesophageal reflux disease (57,1%) and sleep apnea (42,9%). Biochemical tests for cholesterol, triglycerides and blood glucose, presented positive effect, changing from 240,2±36,1 to 162,5±19,1, 215,7±78,1 to 101,0±21,3 and 178,7±55,0 to 96,8±15,3 (mg/dL), respectively. For vitamin B12, hemoglobin and hematocrit, there was no statistical difference in relation to pre and post-operative time; however, was seen a reduction in vitamin B12 in 43 patients (47,2%).
The deficiency of vitamin B12 after six months of surgery could not be observed; this fact can be attributed to the use of nutritional supplements or to the short follow-up time after surgery.
接受减肥手术的患者随着时间推移可能会出现一些并发症，其中贫血是因胃切除导致的重要并发症，会引起铁、叶酸或维生素B12缺乏。
通过比较采用Fobi-Capella（Roux-en-Y）技术进行减肥手术的患者术前和术后（六个月）的情况，确定维生素B12缺乏的发生率以及其他人体测量和生化数据。
对91例接受手术患者的病历进行回顾性和描述性分析。收集了个人信息、手术日期以及术前和术后（六个月）的值、体重减轻情况、合并症、总胆固醇、甘油三酯、血糖、维生素B12、血红蛋白和血细胞比容的血清分析结果。统计分析时，显著性水平设为5%（p<0.05）。
发现体重较术前值减轻了25.0%，平均体重指数从41.2±4.9kg/m²降至30.7±3.9kg/m²。最常见的合并症是呼吸困难（93.4%）、脊柱改变（61.5%）、胃食管反流病（57.1%）和睡眠呼吸暂停（42.9%）。胆固醇、甘油三酯和血糖的生化检测呈现出积极效果，分别从240.2±36.1降至162.5±19.1、从215.7±78.1降至101.0±21.3以及从178.7±55.0降至96.8±15.3（mg/dL）。对于维生素B12、血红蛋白和血细胞比容，术前和术后时间没有统计学差异；然而，43例患者（47.2%）的维生素B12出现了下降。
术后六个月未观察到维生素B12缺乏；这一事实可能归因于营养补充剂的使用或术后随访时间较短。
