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尽管广泛使用了补充剂,但在减重手术后仍会出现长期的铁和维生素 B12 缺乏。

Long-Term Iron and Vitamin B12 Deficiency Are Present after Bariatric Surgery, Despite the Widespread Use of Supplements.

机构信息

Department of Human Sciences and Promotion of the Quality of Life, San Raffaele Open University, 00166 Rome, Italy.

Department of Systems Medicine, Tor Vergata University, 00133 Rome, Italy.

出版信息

Int J Environ Res Public Health. 2021 Apr 25;18(9):4541. doi: 10.3390/ijerph18094541.

Abstract

There are few long-term nutritional studies in subjects undergoing bariatric surgery that have assessed weight regain and nutritional deficiencies. In this study, we report data 8 years after surgery on weight loss, use of dietary supplements and deficit of micronutrients in a cohort of patients from five centres in central and northern Italy. The study group consisted of 52 subjects (age: 38.1 ± 10.6 y, 42 females): 16 patients had Roux-en-Y gastric bypass (RYGB), 25 patients had sleeve gastrectomy (SG) and 11 subjects had adjustable gastric banding (AGB). All three bariatric procedures led to sustained weight loss: the average percentage excess weight loss, defined as weight loss divided by excess weight based on ideal body weight, was 60.6% ± 32.3. Despite good adherence to prescribed supplements, 80.7% of subjects (72.7%, AGB; 76.7%, SG; 93.8 %, RYGB) reported at least one nutritional deficiency: iron (F 64.3% vs. M 30%), vitamin B12 (F 16.6% vs. M 10%), calcium (F 33.3% vs. M 0%) and vitamin D (F 38.1% vs. M 60%). Long-term nutritional deficiencies were greater than the general population among men for iron and among women for vitamin B12.

摘要

在接受减肥手术的受试者中,很少有长期的营养研究评估体重反弹和营养缺乏。在这项研究中,我们报告了意大利中部和北部五个中心的 52 名患者手术后 8 年的减肥、饮食补充剂使用和微量营养素缺乏的数据。研究组包括 52 名患者(年龄:38.1 ± 10.6 岁,42 名女性):16 名患者接受了 Roux-en-Y 胃旁路术(RYGB),25 名患者接受了袖状胃切除术(SG),11 名患者接受了可调节胃束带术(AGB)。所有三种减肥手术都导致了持续的体重减轻:超重体重减轻的平均百分比,定义为体重减轻除以基于理想体重的超重,为 60.6% ± 32.3。尽管很好地遵守了规定的补充剂,但 80.7%的患者(AGB 为 72.7%,SG 为 76.7%,RYGB 为 93.8%)报告至少有一种营养缺乏:铁(F 为 64.3%,M 为 30%),维生素 B12(F 为 16.6%,M 为 10%),钙(F 为 33.3%,M 为 0%)和维生素 D(F 为 38.1%,M 为 60%)。长期营养缺乏在男性中比一般人群更严重,缺铁,在女性中比一般人群更严重,维生素 B12 缺乏。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df98/8123142/287e580486e4/ijerph-18-04541-g001.jpg

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