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选择性髂内动脉覆盖而不进行线圈栓塞的血管内动脉瘤修复的结果。

Outcomes of endovascular aneurysm repair with selective internal iliac artery coverage without coil embolization.

机构信息

Department of Vascular Surgery, Euromedica Blue Cross Hospital, Thessaloniki, Greece.

出版信息

J Vasc Surg. 2012 Aug;56(2):298-303. doi: 10.1016/j.jvs.2011.08.063. Epub 2012 May 8.

Abstract

OBJECTIVE

Endovascular aneurysm repair (EVAR) of abdominal aortic aneurysms (AAAs) that also involve the common iliac artery (CIA) typically is accomplished by endograft limb extension into the external iliac artery (EIA). In order to prevent endoleak, the internal iliac artery (IIA) is usually embolized, or alternatively a branched limb is deployed. However, IIA embolization is associated with longer operative time and increased use of contrast and radiation. It has been our practice not to routinely coil embolize the IIA. The purpose of this study was to present the midterm outcomes of this approach.

METHODS

Between April 1997 and June 2010, 137 patients (130 men; mean age, 70.9 years; range, 45-92 years) underwent EVAR of their AAA and had IIA coverage without coil embolization in 112 patients (no embolization [NE] group) and after coil embolization in 25 patients (coil embolization [CE] group). Anatomic indications for coverage of the IIA without coil embolization included presence of adequate sealing in the distal 5 mm of the CIA, or sealing ring at the origin of the CIA, or IIA diameter <5 mm. Preoperative mean AAA size was 60 ± 14 mm, and mean CIA diameter was 38 ± 13 mm. Postoperative computed tomography (CT) scanning was performed at 1, 6, and 12 months, and yearly thereafter.

RESULTS

Thirty-day mortality was 0.7% (1 of 137 patients). A patient presented with gluteal skin necrosis (0.7%). The incidence of postoperative buttock claudication was not different between the two groups (NE: 15 of 112 patients; CE: 3 of 25 patients; P = .852). Procedure and fluoroscopy time, contrast use, and hospital stay were significantly reduced in the NE group. Patients were followed up for 33 ± 30 months. During follow-up, 44 patients died (32.1%) and in 3 of them (2.2%), death was AAA-related. There was no difference in cumulative survival between the two groups at 1, 2, 3, and 4 years, respectively. Secondary interventions were performed in 20 of 137 patients (14.5%), including three conversions for proximal endoleak. There was no difference between the two groups in the incidence of secondary interventions (NE: 18 of 112 patients; CE: two of 25 patients; P = .301) and freedom from reintervention at 1, 2, 3, and 4 years, respectively. Ten patients (8.9%) from the NE group presented a type II endoleak during follow-up. Seven of them were associated with the covered IIA; none required reintervention.

CONCLUSIONS

Stent graft coverage of the IIA without coil embolization is a safe, simple, and effective maneuver for the treatment of aortoiliac aneurysms, with a low incidence of postoperative complications and reinterventions and acceptable immediate and midterm results.

摘要

目的

腹主动脉瘤(AAA)的血管内修复(EVAR)通常涉及髂总动脉(CIA),需要通过移植物分支延伸到髂外动脉(EIA)。为了防止内漏,通常会对髂内动脉(IIA)进行栓塞,或者部署分支型移植物。然而,IIA 栓塞与更长的手术时间、更多地使用造影剂和辐射有关。我们的做法是不常规对 IIA 进行线圈栓塞。本研究的目的是介绍这种方法的中期结果。

方法

1997 年 4 月至 2010 年 6 月期间,137 例患者(130 例男性;平均年龄 70.9 岁;范围 45-92 岁)接受了 AAA 的 EVAR 治疗,其中 112 例患者(无栓塞[NE]组)和 25 例患者(线圈栓塞[CE]组)的 IIA 被覆盖但未进行线圈栓塞。不进行线圈栓塞覆盖 IIA 的解剖学指征包括 CIA 远端 5mm 处有足够的封闭、CIA 起源处有封闭环或 IIA 直径<5mm。术前平均 AAA 大小为 60±14mm,平均 CIA 直径为 38±13mm。术后 1、6 和 12 个月以及此后每年进行 CT 扫描。

结果

30 天死亡率为 0.7%(137 例患者中有 1 例)。1 例患者出现臀肌皮肤坏死(0.7%)。两组术后臀肌跛行的发生率无差异(NE:112 例患者中有 15 例;CE:25 例患者中有 3 例;P=0.852)。NE 组的手术和透视时间、造影剂使用和住院时间明显减少。患者平均随访 33±30 个月。随访期间,44 例患者死亡(32.1%),其中 3 例(2.2%)与 AAA 相关。两组分别在 1、2、3 和 4 年的累积生存率无差异。137 例患者中有 20 例(14.5%)进行了二次干预,包括 3 例近端内漏的转换。两组间二次干预的发生率(NE:112 例患者中有 18 例;CE:25 例患者中有 2 例;P=0.301)和 1、2、3 和 4 年的免于再次干预率均无差异。NE 组中有 10 例(8.9%)患者在随访期间出现 II 型内漏。其中 7 例与被覆盖的 IIA 有关;均无需再次干预。

结论

不进行线圈栓塞覆盖 IIA 是治疗腹主动脉瘤的一种安全、简单、有效的方法,术后并发症和再次干预的发生率较低,即时和中期结果可接受。

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