Divisions of Pediatric Surgery, Pediatrics and Pathology, Antônio Pedro University Hospital, Federal Fluminense University, Rio de Janeiro, Brazil.
J Pediatr Urol. 2012 Oct;8(5):e51-4. doi: 10.1016/j.jpurol.2012.03.011. Epub 2012 May 8.
A 6-year-old male presented with testicular growth and persistent chronic orchiepididymitis with high inflammatory markers (C reactive protein and erythrocyte sedimentation rate). Biopsies of the testes and epididymides showed bilateral epididymal and testicular granulomata, testicular fibrosis and chronic inflammatory infiltration, and the histological diagnosis was granulomatous orchitis. The symptoms receded with oral corticosteroids. Although rare, granulomatous orchitis is a possible diagnosis in children presenting testicular enlargement. It is important to differentiate it from testicular tumors (if necessary with testicular biopsy) and to investigate its association with systemic vasculitis and infectious diseases.
一位 6 岁男性因睾丸增大和持续性慢性附睾炎-睾丸炎伴高炎症标志物（C 反应蛋白和红细胞沉降率）就诊。睾丸和附睾活检显示双侧附睾和睾丸肉芽肿，睾丸纤维化和慢性炎症浸润，组织学诊断为肉芽肿性睾丸炎。症状随口服皮质类固醇消退。尽管罕见，但肉芽肿性睾丸炎是儿童出现睾丸肿大的可能诊断。重要的是要将其与睾丸肿瘤（如有必要行睾丸活检）区分开来，并调查其与全身血管炎和传染病的关系。
