Chemistry Department, Faculty of Science (boys), Al-Azhar University, Nasr City, Cairo, Egypt.
Appl Biochem Biotechnol. 2012 Jun;167(3):581-94. doi: 10.1007/s12010-012-9709-5. Epub 2012 May 11.
Schiff base ligand (H(3)L) was prepared from the condensation reaction of protochatechualdehyde (3,4-dihydroxybenzaldhyde)with 2-amino phenol. From the direct reaction of the ligand (H(3)L) with Co(II), Ni(II) and Cu(II) chlorides, and Fe(III)and Zn(II)nitrates in 2 M/1 L molar ratio, the five new neutral complexes were prepared. The characterization of the newly formed compounds was done by (1)H NMR, UV-Vis, and IR spectroscopy and elemental analysis. The in vitro antibacterial activity of the metal complexes was studied and compared with that of free ligand.
席夫碱配体（H(3)L）是由原儿茶醛（3,4-二羟基苯甲醛）与 2-氨基苯酚缩合反应制备的。通过配体（H(3)L）与 Co(II)、Ni(II)和 Cu(II)氯化物以及 Fe(III)和 Zn(II)硝酸盐在 2 M/1 L 摩尔比的直接反应，制备了五个新的中性配合物。通过（1）H NMR、UV-Vis 和 IR 光谱以及元素分析对新形成的化合物进行了表征。研究了金属配合物的体外抗菌活性，并与游离配体进行了比较。
