Discipline of Physiotherapy, Faculty of Health Sciences, University of Sydney, Sydney, PO Box 170, Lidcombe, 1825, New South Wales, Australia.
Phys Ther. 2012 Dec;92(12):1556-63. doi: 10.2522/ptj.20110410. Epub 2012 May 10.
The Six-Minute Walk Test (6MWT) is widely used as an outcome measure in exercise rehabilitation. However, the repeatability of the 6MWT performed at home in survivors of a critical illness has not been evaluated.
The purpose of this study was to evaluate, in survivors of a critical illness: (1) the repeatability of the 6MWT performed at home, (2) the effect on estimates of change in functional exercise capacity if only one 6MWT was performed at follow-up assessments, and (3) the relationship between the physical functioning (PF) score of the 36-Item Short-Form Health Survey questionnaire (SF-36) and the 6MWT.
Repeated measures of the 6MWT and SF-36 were obtained.
Eligible participants had an intensive care unit (ICU) length of stay of ≥48 hours and were mechanically ventilated for ≥24 hours. Two 6MWTs and the SF-36 were conducted in participants' homes at weeks 1, 8, and 26 after hospital discharge.
One hundred seventy-three participants completed the study. The participants had a mean age of 57 years (SD=16), a mean Acute Physiology and Chronic Health Evaluation II (APACHE II) score on admission of 19 (SD=10), a mean ICU length of stay of 9 days (SD=8), and a mean mechanical ventilation time of 140 hours (SD=137). Of the 173 participants, 110 performed two 6MWTs at weeks 1, 8, and 26. There were significant mean increases in 6-minute walk distance in the second test of 15 m (P<.0001) at week 1, 13 m (P<.0001) at week 8, and 9 m (P=.04) at week 26. If only one 6MWT was performed at weeks 8 and 26, the estimate of change in 6-minute walk distance from week 1 was 19 m less (P<.001) at both weeks 8 and 26. There was a moderate to strong correlation between SF-36 PF score and 6-minute walk distance at each assessment (week 1: r=.62, P<.001; week 8: r=.55, P<.001; and week 26: r=.47, P<.001).
Some study participants were unable to perform a second 6MWT, and these participants may have differed in important aspects of function compared with those individuals who completed two 6MWTs.
In survivors of a critical illness, the 6MWT in the home environment should be performed twice at each assessment to give an accurate reflection of change in exercise capacity over time. The SF-36 PF score was a strong indicator of 6-minute walk distance in early recovery from a critical illness.
六分钟步行测试（6MWT）被广泛用作运动康复的结果测量。然而，危重病幸存者在家中进行的 6MWT 的可重复性尚未得到评估。
本研究旨在评估危重病幸存者：（1）在家中进行的 6MWT 的可重复性，（2）如果仅在随访评估时进行一次 6MWT，对功能运动能力变化的估计的影响，以及（3）36 项简短健康调查问卷（SF-36）的身体功能（PF）评分与 6MWT 之间的关系。
重复测量 6MWT 和 SF-36。
在参与者出院后第 1、8 和 26 周，在参与者的家中进行了两次 6MWT 和 SF-36。
173 名参与者完成了研究。参与者的平均年龄为 57 岁（SD=16），入院时急性生理学和慢性健康评估 II（APACHE II）评分平均为 19（SD=10），平均 ICU 住院时间为 9 天（SD=8），平均机械通气时间为 140 小时（SD=137）。在 173 名参与者中，有 110 名在第 1、8 和 26 周进行了两次 6MWT。在第 1 周，第二次 6 分钟步行距离增加了 15 米（P<.0001），第 8 周增加了 13 米（P<.0001），第 26 周增加了 9 米（P=.04）。如果仅在第 8 和 26 周进行一次 6MWT，则与第 1 周相比，6 分钟步行距离的变化估计值将减少 19 米（P<.001）。SF-36 PF 评分与每个评估时的 6 分钟步行距离均呈中度至强相关性（第 1 周：r=.62，P<.001；第 8 周：r=.55，P<.001；第 26 周：r=.47，P<.001）。
一些研究参与者无法进行第二次 6MWT，与完成两次 6MWT 的参与者相比，这些参与者在功能方面可能存在重要差异。
在危重病幸存者中，为了准确反映随时间推移运动能力的变化，应在每次评估时在家中环境中进行两次 6MWT。SF-36 PF 评分是危重病后早期 6 分钟步行距离的强有力指标。
