Lin Po-Cheng, Chiou Tzyy-Wen, Liu Po-Yen, Chen Shee-Ping, Wang Hsin-I, Huang Pi-Chun, Lin Shinn-Zong, Harn Horng-Jyh
Center for Neuropsychiatry and Department of Neurosurgery, China Medical University Hospital, Taichung, Taiwan.
J Biomed Biotechnol. 2012;2012:498051. doi: 10.1155/2012/498051. Epub 2012 Apr 22.
Few rejuvenation and antiaging markers are used to evaluate food supplements. We measured three markers in peripheral blood to evaluate the antiaging effects of a food supplement containing placental extract. Samples were evaluated for CD34(+) cells, insulin-like growth factor 1 (IGF1), and telomerase activity, which are all markers related to aging. To control the quality of this food supplement, five active components were monitored. In total, we examined 44 individuals who took the food supplement from 1.2 months to 23 months; the average number of CD34(+) cells was almost 6-fold higher in the experimental group compared with the control group. Food supplement intake did not change serum IGF1 levels significantly. Finally, the average telomerase activity was 30% higher in the subjects taking this food supplement. In summary, our results suggest that the placental extract in the food supplement might contribute to rejuvenation and antiaging.
很少有抗衰和抗衰老标志物用于评估食品补充剂。我们检测了外周血中的三种标志物，以评估一种含胎盘提取物的食品补充剂的抗衰老作用。对样本进行了CD34(+)细胞、胰岛素样生长因子1（IGF1）和端粒酶活性的评估，这些都是与衰老相关的标志物。为控制这种食品补充剂的质量，监测了五种活性成分。我们总共检查了44名服用该食品补充剂1.2个月至23个月的个体；实验组中CD34(+)细胞的平均数量比对照组高出近6倍。摄入食品补充剂并未显著改变血清IGF1水平。最后，服用这种食品补充剂的受试者的平均端粒酶活性高出30%。总之，我们的结果表明，该食品补充剂中的胎盘提取物可能有助于抗衰和抗衰老。
