Faure A, Nemoz C, Claustrat B
Departement Pharmaceutique de Biophysique, Mathématiques et Informatique, Université Claude Bernard, Lyon, France.
Comput Biol Med. 1990;20(5):319-29. doi: 10.1016/0010-4825(90)90011-d.
The mathematical and statistical analysis of biological time series is complex. In view of the necessity to deal with non equidistant data to analyse biological variables, preference is often given to the "cosinor procedure". We propose here a graphical and statistical assistance program for single or multiple cosinor procedure applicable to time series in chronobiology. This program investigates whether a cosine function or a mixture of cosine functions describe the experimental data adequately. The computer program is illustrated on data which have been published in a preceding paper.
生物时间序列的数学和统计分析很复杂。鉴于在分析生物变量时需要处理非等距数据，人们通常更倾向于使用“协方差分析程序”。我们在此提出一个适用于生物钟学时间序列的单变量或多变量协方差分析程序的图形化和统计辅助程序。该程序探究余弦函数或余弦函数的混合是否能充分描述实验数据。通过之前一篇论文中发表的数据对该计算机程序进行了说明。
