Khosravi Alireza, Pourmoghaddas Masoud, Asadi Kourosh, Abdi Ahmadnoor, Gholamrezaei Ali
Assistant Professor, Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
ARYA Atheroscler. 2011 Spring;7(1):24-30.
There is a lack of data in our society on the outcomes, complications, and prognostic factors in patients with coronary artery disease who underwent percutaneous coronary intervention (PCI). We evaluated the success rate, early and late outcomes, and prognostic factors in a referral university center in Isfahan, IRAN.
This prospective cohort study was conducted in Chamran University Hospital in Isfahan (IRAN) from March 2010 to February 2011. Patients consequently were included if they have the indication for emergent or elective PCI. Outcomes included procedural success, complications, and major adverse cardiovascular events (MACE) during hospitalization and 6 months follow-up.
A total of 282 patients (74.1% females) with mean age of 57.0±3.2 years were studied. Most of the patients (89.7%) underwent elective PCI. Angiographic and procedure success rates were 95.7% and 94.6%, respectively. In-hospital MACE included two cases of death (0.7%) and one MI (0.3%); 2/29 (6.9%) of the emergent PCI and 1/253 (0.4%) of the elective PCI cases. MACE during follow-up included three cases of death (1.0%) and two MI (0.7%); 2/252 (0.8%) of the elective PCI and 1/28 (3.5%) of the emergent PCI cases. The overall MACE was calculated as 8 cases (2.8%) which included 5/29 (17.2%) of the emergent and 3/253 (1.1%) of the elective cases; P<0.001. In multivariate analysis, none of the factors including gender, age, emergency of the procedure, lesion type, number of stenotic vessels, or stent type were associated with total MACE (P>0.05).
PCI is performed with an acceptable success rate in our center in Isfahan and mortality and complications are within the range reported by other highly specialized centers in IRAN. Further studies with larger sample size are needed to find predictive factors.
在我们的社会中,关于接受经皮冠状动脉介入治疗(PCI)的冠心病患者的治疗结果、并发症和预后因素的数据匮乏。我们在伊朗伊斯法罕的一所转诊大学中心评估了成功率、早期和晚期结果以及预后因素。
这项前瞻性队列研究于2010年3月至2011年2月在伊朗伊斯法罕的查姆兰大学医院进行。因此,如果患者有急诊或择期PCI的指征,就将其纳入研究。结果包括手术成功率、并发症以及住院期间和6个月随访期间的主要不良心血管事件(MACE)。
共研究了282例患者(74.1%为女性),平均年龄为57.0±3.2岁。大多数患者(89.7%)接受了择期PCI。血管造影和手术成功率分别为95.7%和94.6%。住院期间的MACE包括2例死亡(0.7%)和1例心肌梗死(0.3%);急诊PCI病例中有2/29(6.9%),择期PCI病例中有1/253(0.4%)。随访期间的MACE包括3例死亡(1.0%)和2例心肌梗死(0.7%);择期PCI病例中有2/252(0.8%),急诊PCI病例中有1/28(3.5%)。总体MACE计算为8例(2.8%),其中急诊病例中有5/29(17.2%),择期病例中有3/253(1.1%);P<0.001。在多变量分析中,包括性别、年龄、手术急诊情况、病变类型、狭窄血管数量或支架类型在内的因素均与总体MACE无关(P>0.05)。
在我们位于伊斯法罕的中心,PCI的成功率是可以接受的,死亡率和并发症在伊朗其他高度专业化中心报告的范围内。需要进行更大样本量的进一步研究以找到预测因素。