Department of Cardiovascular Disease, S. Donato Hospital, Arezzo, Italy.
Am Heart J. 2010 Dec;160(6 Suppl):S1-3. doi: 10.1016/j.ahj.2010.10.008.
Despite advances in both the early management and longer-term treatment of acute myocardial infarction, this condition still represents a leading cause of morbidity and mortality in western countries, making essential understanding its determinants. All epidemiologic studies examining prognosis after acute myocardial infarction have used data collected in the midst of the epidemic, possibly giving rise to conflicting results. Hospitalization rates for myocardial infarction have remained relatively stable for the past five decades, in the face of declining coronary heart disease risk factor prevalence and mortality rates, yielding to a paradoxical effect. Many factors like the decrease in severity of such disease and the changes in myocardial infarction definitions may have contributed to such phenomenon. Moreover, because non-ST elevation myocardial infarctions now constitute most of cases in communities, interventions must be designed that recognize this epidemiological reality. At the same time, improved survival in recent decades may have contributed to an increase in the pool of people at risk for developing HF. Thus, the epidemiology and treatment of this condition has not stood still.
尽管在急性心肌梗死的早期管理和长期治疗方面都取得了进展,但在西方国家,这种疾病仍然是发病率和死亡率的主要原因,因此必须深入了解其决定因素。所有研究急性心肌梗死后预后的流行病学研究都使用了在疫情期间收集的数据,这可能导致结果相互矛盾。在过去的五十年里,尽管冠心病危险因素的患病率和死亡率都在下降,但心肌梗死的住院率仍然相对稳定,这产生了一种矛盾的效果。许多因素,如疾病严重程度的降低和心肌梗死定义的变化,可能促成了这种现象。此外,由于非 ST 段抬高型心肌梗死现在构成了社区中大多数病例,因此必须设计出能够认识到这种流行病学现实的干预措施。与此同时,近几十年来生存率的提高可能导致了更多的人面临心力衰竭的风险。因此,这种疾病的流行病学和治疗并没有停滞不前。