Balasubramanian M P
Department of Pharmacology, PGIBMS, University of Madras, Taramani, India.
Cytobios. 1990;63(252):31-9.
Esterase activity of Gigantocotyle explanatum, Ceylonocotyle scoliocoelium and Cotylophoron cotylophorum were localized histochemically in various regions associated with nutrition, viz, integument, pharynx, sucker and gastrodermis. The intensity of the reactions varied in the different regions of the same parasite and also from species to species. The distribution and relative activity of the esterases were investigated and the results reveal that the influence of inhibitors/activators on enzyme activity varied in the different regions. Based on the inhibitory effects it is inferred that carboxylesterases are distributed in the region of the integument, pharynx and gastrodermis, acetylesterases in the suckers and cholinesterase in the subtegumental cells and muscle of these three trematodes.
用组织化学方法对巨大阔盘吸虫、斯氏锡兰吸虫和殖盘殖盘吸虫的酯酶活性在与营养相关的各个区域进行了定位，这些区域包括体表、咽、吸盘和肠皮层。同一寄生虫不同区域的反应强度不同，不同物种之间也存在差异。对酯酶的分布和相对活性进行了研究，结果表明抑制剂/激活剂对酶活性的影响在不同区域有所不同。根据抑制作用推断，羧酸酯酶分布在体表、咽和肠皮层区域，乙酰酯酶分布在吸盘，胆碱酯酶分布在这三种吸虫的皮下细胞和肌肉中。
