大鼠下颌开口反射的延长及一种中枢性肌肉松弛剂（阿夫唑仑）的作用

Extension of the jaw opening reflex and effects of a central muscle relaxant (afloqualone) in the rat.

作者信息

Shohara E, Matsushita K, Hosoi E, Tatsumi Y, Sugimura M

机构信息

Department of Oral and Maxillofacial Surgery, Nara Medical University, Nara, Japan.

出版信息

Dtsch Zahnarztl Z. 1990 Jan;45(1):32-4.

PMID:2257798

Abstract

How widely the jaw opening reflex (JOR) extends was examined in the rat. Recording was done in the anterior (AD) and posterior (PD) digastric, sternohyoid (SH) and sternomastoid (SCM) muscles. Electric stimulation was given to the mandibular incisor pulp. Evoked electromyogram (EMG) activities could be recorded in each muscle. The thresholds for JOR increased from AD to SCM. Intravenously administered afloqualone, a centrally acting muscle relaxant, inhibited both JOR and its parallels promptly and dose-dependently. The possible clinical significance in temporomandibular joint dysfunction will be discussed.

摘要

研究了大鼠下颌开口反射（JOR）的扩展范围。在二腹肌前腹（AD）、二腹肌后腹（PD）、胸骨舌骨肌（SH）和胸锁乳突肌（SCM）中进行记录。对下颌切牙髓进行电刺激。可在每块肌肉中记录诱发肌电图（EMG）活动。JOR的阈值从AD到SCM逐渐升高。静脉注射中枢性肌肉松弛剂阿弗喹酮能迅速且剂量依赖性地抑制JOR及其类似反应。将讨论其在颞下颌关节功能障碍中的潜在临床意义。