Renier J C, Moreau R, Bernat M, Basle M, Jallet P, Minier J F
Rev Rhum Mal Osteoartic. 1979 Apr;46(4):235-41.
The authors studied 20 patients suffering from algodystrophy (23 localizations) by triple scintigraphy with technetium, using pyrophosphate to study the importance of bone changes, marked red blood cells to measure the vascular volume, and pertechnetate to measure the interstitial compartment. These tests were done on the average 1.4 months after the outset of the disease. This work made it possible to demonstrate in the algodystrophy: a pronounced bone hyperfixation that was uneven according to the patients; a frank increase in the vascular volume, notably on the capillary level, and a reduction of the circulatory output (calculated on 4 distal localizations), and an increase of the interstitial compartment higher than that of the vascular volume and corresponding to the edema. These results demonstrate a circulatory stasis. In 4 patients treatment with calcitonine reduced the vascular volume but not the bone hyperfixation. In 1 patient, treatment with pindolol reduced the bone hyperfixation and the vascular volume. The authors underline the advantage of such methods in creating a better knowledge of the physiopathology of algodystrophies and effective means of treating them.
作者通过使用焦磷酸盐的锝三重闪烁扫描术研究了20例患有反射性交感神经营养不良（23个部位）的患者，利用焦磷酸盐研究骨变化的重要性，标记红细胞以测量血容量，并用高锝酸盐测量间质腔隙。这些检查平均在疾病开始后1.4个月进行。这项工作使得在反射性交感神经营养不良中得以证实：明显的骨过度摄取，且因患者而异；血容量明显增加，尤其是在毛细血管水平，循环输出减少（根据4个远端部位计算），间质腔隙增加且高于血容量的增加，并与水肿相对应。这些结果表明存在循环淤滞。在4例患者中，降钙素治疗降低了血容量，但未降低骨过度摄取。在1例患者中，吲哚洛尔治疗降低了骨过度摄取和血容量。作者强调了此类方法在更好地了解反射性交感神经营养不良的病理生理学及有效治疗手段方面的优势。
