激素治疗对绝经后妇女嗓音质量的影响。
The impact of hormone therapy on vocal quality in postmenopausal women.
机构信息
Department of Otorhinolaryngology, Logopaedic and Audiologic Sciences, Ghent University, Ghent, Belgium.
出版信息
J Voice. 2012 Sep;26(5):671.e1-7. doi: 10.1016/j.jvoice.2011.11.011. Epub 2012 May 11.
OBJECTIVES
The main purpose of this study was to investigate the impact of hormone therapy (HT) on vocal characteristics in postmenopausal women by comparing postmenopausal women with HT (n=59) and postmenopausal women without HT (n=46). The second purpose was to investigate the differences in vocal characteristics between two types of HT: estrogen therapy (ET) and estrogen-progestogen therapy (E-PT).
METHODS
To determine the vocal characteristics in both groups, objective (aerodynamic measurements, vocal range measurements, acoustic analysis, and a determination of the dysphonia severity index) and subjective assessment techniques (perceptual evaluation, videostroboscopic evaluation, and voice handicap index) were used.
RESULTS
The postmenopausal women without HT showed a significantly lower speaking fundamental frequency and were able to phonate lower compared with postmenopausal women with HT. No differences in vocal characteristics were found between postmenopausal women with ET and postmenopausal women with E-PT.
CONCLUSION
HT seems to counteract the vocal changes caused by menopause. The type of HT did not affect the outcome in this study.
目的
本研究的主要目的是通过比较接受激素治疗（HT）的绝经后妇女（n=59）和未接受 HT 的绝经后妇女（n=46），探讨 HT 对绝经后妇女嗓音特征的影响。第二个目的是研究两种 HT（雌激素治疗（ET）和雌孕激素治疗（E-PT））之间嗓音特征的差异。
方法
为了确定两组的嗓音特征，使用了客观（空气动力学测量、音域测量、声学分析和嗓音障碍严重指数的测定）和主观评估技术（感知评估、频闪喉镜评估和嗓音障碍指数）。
结果
未接受 HT 的绝经后妇女的基频明显较低，能够比接受 HT 的绝经后妇女发更低的音。接受 ET 和 E-PT 的绝经后妇女之间的嗓音特征没有差异。
结论
HT 似乎可以抵消绝经引起的嗓音变化。本研究中 HT 的类型并未影响结果。
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