The Heart Centre, Royal Victoria Hospital, Belfast, United Kingdom.
Resuscitation. 2012 Dec;83(12):1438-43. doi: 10.1016/j.resuscitation.2012.04.018. Epub 2012 May 9.
Most commercially available defibrillators utilise a high tilt waveform. Work in atrial fibrillation has shown improved defibrillation success using low tilt waveforms. We hypothesise that a novel low tilt biphasic waveform will be non-inferior to a standard tilt waveform whilst delivering lower energy for the defibrillation of ventricular arrhythmias.
Patients in cardiac arrest who experienced ventricular arrhythmias received shocks from a novel low tilt waveform defibrillator at 120J or a standard tilt waveform defibrillator at 150J. Resuscitation guidelines were followed as per Resuscitation Council UK, 2005. A shock was successful when the ventricular arrhythmia was terminated for ≥ 5s following shock delivery.
A total of 113 cardiac arrest cases were included. The low tilt device was used for 56 cases and the standard tilt device for 57 cases. The presenting rhythm was ventricular fibrillation (VF) in 71.7% (81/113), pulseless electrical activity (PEA) in 15.9% (18/113), ventricular tachycardia (VT) in 9.7% (11/113), asystole in 1.8% (2/113) and narrow complex rhythm in 0.9% (1/113). The low tilt device resulted in first shock success in 86% (48/56 cases) vs. the standard tilt device first shock success of 77% (44/57 cases). There was no significant difference in first shock success between the two devices (p=0.36).
The low tilt waveform used in this study demonstrated first shock success rates in keeping with a commercially available high tilt defibrillator which could result in less myocardial damage due to reduced energy requirements.
大多数市售的除颤器采用高倾斜波形。在心房颤动中的研究表明,使用低倾斜波形可提高除颤成功率。我们假设一种新型的低倾斜双相波形在为室性心律失常除颤时,将不逊于标准倾斜波形,同时所需能量更低。
心脏骤停并发生室性心律失常的患者接受新型低倾斜波形除颤器 120J 或标准倾斜波形除颤器 150J 电击。按照 2005 年英国复苏委员会的复苏指南进行复苏。当电击后室性心律失常终止≥5s 时,电击成功。
共纳入 113 例心脏骤停病例。56 例使用低倾斜设备,57 例使用标准倾斜设备。初始节律为室颤(VF)的占 71.7%(81/113),无脉电活动(PEA)占 15.9%(18/113),室性心动过速(VT)占 9.7%(11/113),心搏停止占 1.8%(2/113),窄复合节律占 0.9%(1/113)。低倾斜设备首次电击成功的比例为 86%(48/56 例),标准倾斜设备为 77%(44/57 例)。两种设备首次电击成功率无显著差异(p=0.36)。
本研究中使用的低倾斜波形与市售的高倾斜除颤器具有相似的首次电击成功率,可因降低能量需求而减少心肌损伤。