Diepgen T L, Simon M
Dermatologische Universitäts-Klinik Erlangen.
Hautarzt. 1990 Oct;41(10):574-7.
A 13-year-old girl had a bird-like face, deficiency of the subcutaneous fatty tissue, dry, thin, transparent and wrinkled skin, especially on the hands and feet, prominent veins and telangiectasia and mottled hyper-pigmentation. X-ray studies revealed acro-osteolysis of the hands and feet. The clinical features corresponded well with Gottron-type acrogeria. The clinical symptoms of premature ageing syndromes, such as progeria, lipodystrophia totalis, Cockayne syndrome, metageria and acrogeria are summarized briefly and compared with the clinical picture observed in our patient.
一名13岁女孩面容如鸟，皮下脂肪组织缺乏，皮肤干燥、薄、透明且有皱纹，尤其是手脚部位，静脉突出、有毛细血管扩张和斑驳的色素沉着。X线检查显示手脚有肢端骨质溶解。临床特征与Gottron型肢端早老症高度相符。早衰综合征的临床症状，如早老症、全身性脂肪营养不良、科凯恩综合征、中年早衰和肢端早老症，在此简要总结并与我们患者的临床表现进行比较。
