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后腹腔镜肾上腺切除术治疗嗜铬细胞瘤:与开放手术的比较

Retroperitoneoscopic adrenalectomy for pheochromocytoma: comparison with open surgery.

作者信息

Hemal Ashok K, Kumar Rajeev, Misra Mahesh C, Gupta Narmada P, Chumber Sunil

机构信息

Department of Urology, All India Institute of Medical Sciences, Ansari Nugar, New Delhi, India.

出版信息

JSLS. 2003 Oct-Dec;7(4):341-5.

Abstract

OBJECTIVES

To evaluate the feasibility of the retroperitoneoscopic approach to adrenalectomy for pheochromocytoma and to compare it with the open retroperitoneal approach.

METHODS

Twelve retroperitoneoscopic adrenalectomies for pheochromocytomas were performed in 10 patients at our center between January 1996 and January 2001. Two patients underwent simultaneous bilateral surgeries. These were retrospectively compared with open adrenalectomy for pheochromocytoma through the extraperitoneal flank approach in 6 patients with 7 adrenalectomies, conducted during the same period.

RESULTS

Retroperitoneoscopic adrenalectomy could be successfully performed in 11 cases with 1 conversion to open surgery. Mean operative time was 151 minutes (range, 90 to 200 min). This was comparable to the time for the open surgery group, 169 minutes (range, 85 to 270 min). However, the mean blood loss of 140 mL (range, 30 to 300 mL), hospital stay of 4.4 days, and analgesia doses required (3.3) were significantly lower than those for the open surgery group (592 mL, 9.8 days, and 8.1 doses, respectively). No significant intraoperative hypertensive crises occurred in either group.

CONCLUSIONS

Retroperitoneoscopy is a safe and feasible option for adrenalectomy for pheochromocytoma. It requires shorter operative time, less postoperative analgesia, a shorter hospitalization, and blood loss is less. Although retroperitoneoscopy is widely practiced for other adrenal tumors, it should now also be considered for pheochromocytomas.

摘要

目的

评估后腹腔镜肾上腺切除术治疗嗜铬细胞瘤的可行性,并与开放后腹膜途径进行比较。

方法

1996年1月至2001年1月,我们中心对10例患者实施了12例后腹腔镜嗜铬细胞瘤肾上腺切除术。2例患者同期进行了双侧手术。将这些病例与同期通过腹膜外侧面途径对6例患者实施7例开放嗜铬细胞瘤肾上腺切除术的病例进行回顾性比较。

结果

11例后腹腔镜肾上腺切除术成功完成,1例中转开放手术。平均手术时间为151分钟(范围90至200分钟)。这与开放手术组的时间相当,开放手术组平均手术时间为169分钟(范围85至270分钟)。然而,后腹腔镜组平均失血量为140毫升(范围30至300毫升)、住院时间为4.4天以及所需镇痛剂量为3.3,均显著低于开放手术组(分别为592毫升、9.8天和8.1剂)。两组术中均未发生明显的高血压危象。

结论

后腹腔镜手术是治疗嗜铬细胞瘤肾上腺切除术的一种安全可行的选择。它所需手术时间更短、术后镇痛更少、住院时间更短且失血量更少。尽管后腹腔镜手术在其他肾上腺肿瘤中广泛应用,但现在对于嗜铬细胞瘤也应予以考虑。

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