Meier Larissa, Stange Rainer, Michalsen Andreas, Uehleke Bernhard
Immanuel Hospital, Department of Complementary and Integrative Medicine, Charité University Medical Centre, Institute for Social Medicine, Epidemiology and Health Economics, Berlin, Germany.
Forsch Komplementmed. 2012;19(2):75-9. doi: 10.1159/000338076. Epub 2012 Apr 19.
External application of clay facial masks is a cosmetic procedure generally used to reduce skin lesions and to improve overall skin condition.
Collecting pilot data about self-treatment with clay jojoba oil masks on participants with acne-prone, lesioned skin and acne.
Open, prospective, observational pilot study: Participants received written information, instructions, and questionnaires without direct contact with the study physician. For 6 weeks, they applied the masks 2-3 times per week. The primary outcome is the difference of skin lesions: baseline vs. after 6 weeks.
194 participants (192 female, 2 male, mean age (± SE) (32.3 ± 0.7 years) returned questionnaires and diaries. 133 of these participants returned complete and precise lesion counts (per-protocol (PP) collective). A 54% mean reduction in total lesion count was observed after 6 weeks of treatment with clay facial mask. Both inflammatory and non-inflammatory skin lesions were reduced significantly after treatment compared to baseline: Median counts (MC) of pustules per affected participant were reduced from 7.0 ± 0.9 to 3.0 ± 0.5 (mean individual reduction (MIR) = 49.4%), the MC of the papules from 3.5 ± 2.2 to 1.0 ± 0.4 (MIR = 57.3%), the MC of cysts from 2.0 ± 0.8 to 0.5 ± 0.4 (MIR = 68.6%) and the MC of comedones from 26.5 ± 6.3 to 16.0 ± 4.0 (MIR = 39.1%). DLQI-average score decreased from 5.0 ± 4.5 (mean ± SE) before to 2.1 ± 2.8 after treatment.
The present study gives preliminary evidence that healing clay jojoba oil facial masks can be effective treatment for lesioned skin and mild acne vulgaris.
外用黏土面膜是一种常用于减少皮肤损伤和改善整体皮肤状况的美容程序。
收集关于使用黏土荷荷巴油面膜对易长痤疮、有皮损的皮肤和痤疮患者进行自我治疗的初步数据。
开放性、前瞻性、观察性试点研究:参与者在不与研究医生直接接触的情况下收到书面信息、说明和问卷。为期6周,他们每周使用面膜2 - 3次。主要结局是皮肤损伤的差异:基线与6周后。
194名参与者(192名女性,2名男性,平均年龄(±标准误)(32.3±0.7岁))返回了问卷和日记。其中133名参与者返回了完整且精确的损伤计数(符合方案(PP)群体)。使用黏土面膜治疗6周后,观察到总损伤计数平均减少了54%。与基线相比,治疗后炎性和非炎性皮肤损伤均显著减少:每个受影响参与者脓疱的中位数计数(MC)从7.0±0.9降至3.0±0.5(平均个体减少(MIR)=49.4%),丘疹的MC从3.5±2.2降至1.0±0.4(MIR = 57.3%),囊肿的MC从2.0±0.8降至0.5±0.4(MIR = 68.6%),粉刺的MC从26.5±6.3降至16.0±4.0(MIR = 39.1%)。皮肤病生活质量指数(DLQI)平均评分从治疗前的5.0±4.5(平均值±标准误)降至治疗后的2.1±2.8。
本研究提供了初步证据,表明愈合黏土荷荷巴油面膜对有皮损的皮肤和轻度寻常痤疮可能是有效的治疗方法。