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[胎儿-母体界面。从免疫学角度对其组成部分的描述]

[The fetal-maternal interface. Description of its elements from an immunologic perspective].

作者信息

Vinatier D, Monnier J C

机构信息

Service de Gynécologie-Obstétrique, C.H.U., Lille.

出版信息

J Gynecol Obstet Biol Reprod (Paris). 1990;19(6):691-700.

PMID:2258587
Abstract

The authors describe the different elements that can change the immunological response at the feto-maternal interface having studied the increasingly large literature on the subject. They consider first the nature of the interface and how trophoblastic antigens occur and then they point out the type and the role played by the different numerous decidual cells that take part in recognising, activating and regulating the immune system there. This general review is justified because local immunological phenomena seem to be important for the survival and the development of the feto-placental unit. They are also for immuno-suppressant mechanisms and immuno-tropic mechanisms. These phenomena, however important they may be, make it necessary to recognise one or more embryonic or trophoblastic antigens acting on the maternal immunological system.

摘要

作者在研究了关于该主题日益增多的文献后,描述了可改变母胎界面免疫反应的不同因素。他们首先考虑界面的性质以及滋养层抗原的出现方式,然后指出参与识别、激活和调节那里免疫系统的众多不同蜕膜细胞的类型及作用。这篇综述是合理的,因为局部免疫现象似乎对胎儿 - 胎盘单位的存活和发育很重要。这些现象对于免疫抑制机制和免疫趋向机制也很重要。然而,无论这些现象多么重要,都有必要识别一种或多种作用于母体免疫系统的胚胎或滋养层抗原。

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