Shelukhina E M, Shenkman L S, Rozina E E, Marennikova S S
Vopr Virusol. 1979 Jul-Aug(4):368-72.
Until recently, virus carrier state in the absence of overt clinical infection has been known for only one species of orthopoxviruses, namely, ectromelia virus. The paper describes the results of the modelling of asypmtomatic infection caused by monkeypox, cowpox, and ratpox viruses. Persistence of these viruses up to 6 weeks in animals (hamsters, cotton and white rats) with experimental asymptomatic infection as well as in apparently normal naturally infected white rats was established by isolation of virus from the organs of these animals. These results suggest that asymptomatic virus carrier state may occur both with ectromelia and a number of other orthopoxviruses. The mechanism may be of ecological importance, providing for circulation of these viruses and their preservation as biological species in nature.
直到最近，在没有明显临床感染的情况下，病毒携带状态仅在一种正痘病毒，即鼠痘病毒中被知晓。本文描述了由猴痘、牛痘和大鼠痘病毒引起的无症状感染的建模结果。通过从这些动物的器官中分离病毒，证实了这些病毒在实验性无症状感染的动物（仓鼠、豚鼠和白鼠）以及明显正常的自然感染白鼠中可持续存在长达6周。这些结果表明，无症状病毒携带状态可能在鼠痘以及其他一些正痘病毒中出现。该机制可能具有重要的生态学意义，有助于这些病毒的传播以及它们作为自然界生物物种的保存。
