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病理性近视的高穿透力光学相干断层扫描形态学分析。

Morphologic analysis in pathologic myopia using high-penetration optical coherence tomography.

机构信息

Department of Ophthalmology, Fukushima Medical University School of Medicine, Fukushima, Japan.

出版信息

Invest Ophthalmol Vis Sci. 2012 Jun 20;53(7):3834-8. doi: 10.1167/iovs.12-9811.

Abstract

PURPOSE

We evaluated retrospectively the morphologic choroidal and scleral characteristics in eyes with pathologic myopia using high-penetration optical coherence tomography (HP-OCT) or swept-source OCT (SS-OCT).

METHODS

The subfoveal choroidal and scleral thicknesses were measured using the prototype HP-OCT with a 1060 nm light source. We also measured the scleral thickness 3 mm superior, inferior, nasal, and temporal to the fovea on the horizontal and vertical OCT sections. The axial length (AL) in all eyes was measured using optical biometry.

RESULTS

We examined 58 eyes of 35 patients (7 men and 28 women, mean age 65.5 years) with an AL exceeding 26.5 mm. The mean AL was 29.0 ± 1.4 mm. The full-thickness choroid and sclera were visualized in all eyes. The mean subfoveal choroidal and scleral thicknesses were 52 ± 38 and 335 ± 130 μm, respectively. The mean scleral thicknesses 3 mm superior, inferior, nasal, and temporal to the fovea were 266 ± 78 (n = 57), 259 ± 72 (n = 56), 324 ± 109 (n = 39), and 253 ± 79 (n = 58) μm, respectively. The subfoveal sclera was thicker than 3 mm outside the fovea (P < 0.05, for each comparison).

CONCLUSIONS

The full-thickness choroid and sclera in all eyes with pathologic myopia were visualized using a prototype HP-OCT. The subfoveal sclera was thicker than 3 mm outside the fovea. HP-OCT is a useful tool for morphologic analyses of pathologic myopia.

摘要

目的

我们使用高穿透光学相干断层扫描(HP-OCT)或扫频源光学相干断层扫描(SS-OCT)对病理性近视眼的脉络膜和巩膜形态特征进行回顾性评估。

方法

使用原型 HP-OCT 测量黄斑下脉络膜和巩膜的厚度,光源为 1060nm。我们还在水平和垂直 OCT 切片上测量了黄斑上下、鼻侧和颞侧 3mm 处的巩膜厚度。所有眼的眼轴(AL)均使用光学生物测量法测量。

结果

我们检查了 35 名患者(7 名男性和 28 名女性,平均年龄 65.5 岁)的 58 只眼,其 AL 超过 26.5mm。平均 AL 为 29.0±1.4mm。所有眼均能显示全层脉络膜和巩膜。黄斑下脉络膜和巩膜的平均厚度分别为 52±38μm 和 335±130μm。黄斑上下、鼻侧和颞侧 3mm 处的巩膜平均厚度分别为 266±78μm(n=57)、259±72μm(n=56)、324±109μm(n=39)和 253±79μm(n=58)。黄斑下巩膜厚度大于 3mm 处(P<0.05,每次比较)。

结论

病理性近视患者的全层脉络膜和巩膜均能通过原型 HP-OCT 显示。黄斑下巩膜厚度大于 3mm 处。HP-OCT 是病理性近视形态分析的有用工具。

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