• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

2-氨基-6-（二甲基氨基）吡啶-3,5-二甲腈

2-Amino-6-(dimethyl-amino)pyridine-3,5-dicarbonitrile.

作者信息

Mohamed Shaaban K, Soliman Ahmed M, Abdel-Raheem Eman M M, Saeed Sohail, Wong Wing-Tak

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2012 May 1;68(Pt 5):o1532. doi: 10.1107/S1600536812017278. Epub 2012 Apr 25.

DOI:10.1107/S1600536812017278
PMID:22590396
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3344634/
Abstract

The title compound, C(9)H(9)N(5), is slightly twisted from planarity, with a maximum deviation of 0.0285 (13) Å from the pyridine plane for the C atom bearing the amino group. The cyano groups are on different sides of the pyridine plane, with C- and N-atom deviations of 0.072 (3)/0.124 (4) and -0.228 (4)/-0.409 (5) Å from the pyridine plane. In the crystal, N-H⋯N and C-H⋯N hydrogen bonds connect the mol-ecules into zigzag chains running along the c axis.

摘要

标题化合物C(9)H(9)N(5)略微偏离平面，带有氨基的C原子与吡啶平面的最大偏差为0.0285 (13) Å。氰基位于吡啶平面的不同侧，C原子和N原子与吡啶平面的偏差分别为0.072 (3)/0.124 (4)和 -0.228 (4)/-0.409 (5) Å。在晶体中，N-H⋯N和C-H⋯N氢键将分子连接成沿c轴延伸的锯齿链。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57cc/3344634/6a50a475987d/e-68-o1532-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57cc/3344634/6a50a475987d/e-68-o1532-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57cc/3344634/6a50a475987d/e-68-o1532-fig1.jpg

相似文献

1
2-Amino-6-(dimethyl-amino)pyridine-3,5-dicarbonitrile.2-氨基-6-（二甲基氨基）吡啶-3,5-二甲腈
Acta Crystallogr Sect E Struct Rep Online. 2012 May 1;68(Pt 5):o1532. doi: 10.1107/S1600536812017278. Epub 2012 Apr 25.
2
4-(Methyl-amino)pyridine.4-（甲氨基）吡啶
Acta Crystallogr Sect E Struct Rep Online. 2010 Mar 13;66(Pt 4):o823. doi: 10.1107/S1600536810008986.
3
2-(3-Cyano-4-{7-[1-(2-hy-droxy-eth-yl)-3,3-dimethyl-indolin-2-yl-idene]hepta-1,3,5-trien-yl}-5,5-dimethyl-2,5-dihydro-furan-2-yl-idene)malononitrile.2-（3-氰基-4-{7-[1-（2-羟乙基）-3,3-二甲基-吲哚啉-2-亚基]庚-1,3,5-三烯基}-5,5-二甲基-2,5-二氢呋喃-2-亚基）丙二腈
Acta Crystallogr Sect E Struct Rep Online. 2011 Nov;67(Pt 11):o3026. doi: 10.1107/S1600536811042036. Epub 2011 Oct 22.
4
Dimethyl 4-(3,4-dimethoxy-phen-yl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxyl-ate.4-(3,4-二甲氧基苯基)-2,6-二甲基-1,4-二氢吡啶-3,5-二甲酸二甲酯
Acta Crystallogr Sect E Struct Rep Online. 2010 May 15;66(Pt 6):o1355-6. doi: 10.1107/S160053681001679X.
5
(E)-2-Amino-4-(3,3-dimethyl-2-oxobutyl-idene)-1-[2-(2-hy-droxy-eth-oxy)eth-yl]-6-methyl-1,4-dihydro-pyridine-3-carbo-nitrile.（E）-2-氨基-4-（3,3-二甲基-2-氧代丁基亚甲基）-1-[2-（2-羟基乙氧基）乙基]-6-甲基-1,4-二氢吡啶-3-甲腈
Acta Crystallogr Sect E Struct Rep Online. 2012 Aug 1;68(Pt 8):o2572. doi: 10.1107/S160053681203334X. Epub 2012 Jul 28.
6
2-Amino-5-chloro-pyridine-fumaric acid (1/2).2-氨基-5-氯吡啶-富马酸（1/2）
Acta Crystallogr Sect E Struct Rep Online. 2010 May 22;66(Pt 6):o1416-7. doi: 10.1107/S1600536810018192.
7
3-Amino-1-(4-bromo-phen-yl)-9,10-dihydro-phenanthrene-2,4-dicarbonitrile.3-氨基-1-(4-溴苯基)-9,10-二氢菲-2,4-二甲腈
Acta Crystallogr Sect E Struct Rep Online. 2011 Oct 1;67(Pt 10):o2745. doi: 10.1107/S1600536811038517. Epub 2011 Sep 30.
8
Ethyl 3-amino-4H-thieno[2,3-b]pyridine-2-carboxyl-ate.3-氨基-4H-噻吩并[2,3-b]吡啶-2-羧酸乙酯
Acta Crystallogr Sect E Struct Rep Online. 2008 Dec 3;65(Pt 1):o9. doi: 10.1107/S1600536808039974.
9
2-Amino-5-chloro-pyridine-benzoic acid (1/1).2-氨基-5-氯吡啶-苯甲酸（1/1）
Acta Crystallogr Sect E Struct Rep Online. 2010 Feb 10;66(Pt 3):o578. doi: 10.1107/S1600536810004447.
10
4,4-Dimethyl-3,4-dihydro-pyrido[2',3':3,4]pyrazolo-[1,5-a][1,3,5]triazin-2-amine ethanol monosolvate.4,4-二甲基-3,4-二氢-吡啶并[2',3':3,4]吡唑并-[1,5-a][1,3,5]三嗪-2-胺乙醇单溶剂合物
Acta Crystallogr Sect E Struct Rep Online. 2010 Dec 11;67(Pt 1):o83-4. doi: 10.1107/S160053681005097X.

本文引用的文献

1
2-(Piperidin-1-yl)-6-(1H-pyrrol-1-yl)pyridine-3,5-dicarbonitrile.2-（哌啶-1-基）-6-（1H-吡咯-1-基）吡啶-3,5-二甲腈
Acta Crystallogr Sect E Struct Rep Online. 2012 Apr 1;68(Pt 4):o938. doi: 10.1107/S1600536812008586. Epub 2012 Mar 3.
2
2-(Morpholin-4-yl)-6-(1H-pyrrol-1-yl)-pyridine-3,5-dicarbonitrile.2-（吗啉-4-基）-6-（1H-吡咯-1-基）-吡啶-3,5-二甲腈
Acta Crystallogr Sect E Struct Rep Online. 2012 Mar 1;68(Pt 3):o885-6. doi: 10.1107/S160053681200815X. Epub 2012 Feb 29.
3
Synthesis and biological activity of dihydroimidazole and 3,4-dihydrobenzo[4,5]imidazo[1,2-a][1,3,5]triazins.
二氢咪唑和 3,4-二氢苯并[4,5]咪唑并[1,2-a][1,3,5]三嗪的合成与生物活性。
Eur J Med Chem. 2012 Jan;47(1):138-42. doi: 10.1016/j.ejmech.2011.10.034. Epub 2011 Oct 25.
4
Anti-inflammatory and analgesic activities of some newly synthesized pyridinedicarbonitrile and benzopyranopyridine derivatives.一些新合成的吡啶二腈和苯并吡喃并吡啶衍生物的抗炎和镇痛活性
Acta Pharm. 2008 Jun;58(2):175-86. doi: 10.2478/v10007-008-0005-4.
5
A short history of SHELX.SHELX简史。
Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22. doi: 10.1107/S0108767307043930. Epub 2007 Dec 21.
6
Discovery of novel and selective IKK-beta serine-threonine protein kinase inhibitors. Part 1.
Bioorg Med Chem Lett. 2003 Mar 10;13(5):913-8. doi: 10.1016/s0960-894x(02)01046-6.
7
Ionization behaviour and tautomerism-dependent lipophilicity of pyridine-2(1H)-one cardiotonic agents.
Bioorg Med Chem. 2000 May;8(5):909-16. doi: 10.1016/s0968-0896(00)00025-0.