Weischer C H, Greve J
Zentralbl Bakteriol B. 1979 May;168(3-4):266-72.
Female rats were continuously exposed for 3 months to an aerosol containing 50 micrograms/m3 Cadmium-Oxyd and 1.25 mg/m3 Zinc-Oxyd. Our results were compared with those of Prigge (1977), who studied the CdO-toxicity under equal conditions. Inour investigations we studied with clinical and clinico-chemical methods a possible protective effect of ZnO on the Cd-toxicity, given simultanously. A protective effect of ZnO on the Cd-toxicity was evident in out investigations in form of a reduced deposition of Cd in lungs, in livers and kidneys. A reduction of the cadmium-induced hyperplasia of lungs was a remarkable sign for a protective action of Zn. There are some criterions, that Zn, given simultaneously in the studied concentrations, can inhibit the Cd-induced disorder of function in kidneys.
将雌性大鼠连续3个月暴露于含有50微克/立方米氧化镉和1.25毫克/立方米氧化锌的气溶胶中。我们的结果与Prigge（1977年）的结果进行了比较，他在相同条件下研究了氧化镉的毒性。在我们的研究中，我们用临床和临床化学方法研究了同时给予氧化锌对镉毒性的可能保护作用。在我们的研究中，氧化锌对镉毒性的保护作用明显表现为肺、肝脏和肾脏中镉沉积的减少。镉诱导的肺增生减少是锌具有保护作用的一个显著标志。有一些标准表明，在所研究的浓度下同时给予锌可以抑制镉诱导的肾脏功能紊乱。
